Personal profile
Biography
Dr Mahboobeh (Mabi) Behruznia is a Research Fellow in the McNally Group at the University of Birmingham, where she investigates real-time genomic-informed diagnosis of pathogens and personalised antimicrobial approaches to infections in acute care settings using metagenomic analysis. She completed her PhD in 2021 at the Australian National University, focusing on the genetic structure of Escherichia coli strains from septic tanks in Australia. Following her doctoral studies, Dr Behruznia worked as a postdoctoral fellow at the University of Canberra, investigating the prevalence of antimicrobial-resistant bacteria in meat samples in Australia. She later joined Nottingham Trent University, where her research delved into Mycobacterium tuberculosis pangenome and evolution. Dr Behruznia holds a Master’s in Microbiology from Shahid Beheshti University and a Bachelor’s in Biotechnology from Shahed University, Iran. Before her academic career, she also gained industry experience working as a Quality Assurance Specialist.
Research interests
- Applying metagenomic approaches for real-time clinical diagnostics of microbial pathogens, including the detection of antimicrobial resistance profiles, to enhance pathogen surveillance and improve patient outcomes (Metagenomics and sequencing).
- Exploring bacterial diversity and evolution through pangenomic analyses and advanced bioinformatics, aiming to uncover genetic variations and evolutionary patterns within microbial species (Genomics and bioinformatics).
- Investigating antimicrobial resistance in bacteria and its impact on human health and environmental sustainability (Antimicrobial Resistance and genome sequencing)
Education/Academic qualification
Doctor of Philosophy, Genetic structure of Escherichia coli strains isolated from septic tanks in the Canberra region, Australian National University
Nov 2016 → Dec 2021
Award Date: 15 Dec 2021
Master in Science, Bioremediation of oil-contaminated soils with naturally oil-degrading bacteria, Shahid Beheshti University
Aug 2010 → Nov 2012
Award Date: 1 Nov 2012
Bachelor of Science, Shahed University
Aug 2006 → Jul 2010
Award Date: 1 Jul 2010
Keywords
- QH426 Genetics
- Metagenomics
- RB Pathology
- Antimicrobial Resistance (AMR)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 6 Clean Water and Sanitation
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Collaborations and top research areas from the last five years
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P33 Metagenomic sequencing of sputum enables accurate, non-invasive diagnosis of community-acquired pneumonia
Behruznia, M., Cumly, N., Quarton, S., McGee, K., Thickett, D., Parekh, D., Sapey, E. & McNally, A., 4 Dec 2025, In: JAC-Antimicrobial Resistance. 7, Supplement_4, p. iv16-iv17 2 p., dlaf230.040.Research output: Contribution to journal › Abstract › peer-review
Open AccessFile10 Downloads (Pure) -
The Mycobacterium tuberculosis complex pangenome is small and shaped by sub-lineage-specific regions of difference
Behruznia, M., Marin, M., Whiley, D. J., Farhat, M. R., Thomas, J. C., Domingo-Sananes, M. R. & Meehan, C. J., 5 Sept 2025, (E-pub ahead of print) In: eLife. 13, 19 p., RP97870.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Diversity of antimicrobial-resistant bacteria isolated from Australian chicken and pork meat
Dixit, O. V., Behruznia, M., Preuss, A. L. & O'Brien, C., 19 Feb 2024, In: Frontiers in Microbiology. 15, 1347597.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Downloads (Pure) -
pQEB1: a hospital outbreak plasmid lineage carrying blaKPC-2.
Moran, R. A., Behruznia, M., Holden, E., Garvey, M. I. & McNally, A., 2 Sept 2024, In: Microbial Genomics. 10, 9, 001291.Research output: Contribution to journal › Article › peer-review
Open AccessFile63 Downloads (Pure) -
The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli
James, B., Reesaul, H., Kashif, S., Behruznia, M., Meehan, C. J., Domingo-Sananes, M. & Hubbard, A. T. M., 17 Jul 2024, In: npj Antimicrobials and Resistance. 2, 19.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Downloads (Pure)