Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Laura Kirton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Research output
- 6 Article
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A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models for individual risk-part 1: binary outcomes
Riley, R. D., Collins, G. S., Whittle, R., Archer, L., Snell, K. I. E., Dhiman, P., Kirton, L., Legha, A., Liu, X., Denniston, A. K., Harrell, F. E., Wynants, L., Martin, G. P. & Ensor, J., 8 Jul 2025, In: Diagnostic and Prognostic Research. 9, 1, 17 p., 14.Research output: Contribution to journal › Article › peer-review
Open AccessFile90 Downloads (Pure) -
Importance of sample size on the quality and utility of AI-based prediction models for healthcare
Riley, R. D., Ensor, J., Snell, K. I. E., Archer, L., Whittle, R., Dhiman, P., Alderman, J., Liu, X., Kirton, L., Manson-Whitton, J., van Smeden, M., Nirantharakumar, K., Denniston, A. K., Van Calster, B. & Collins, G., 2 Jun 2025, (E-pub ahead of print) In: The Lancet Digital Health. 100857.Research output: Contribution to journal › Article › peer-review
Open AccessFile476 Downloads (Pure) -
Uncertainty of risk estimates from clinical prediction models: rationale, challenges, and approaches
Riley, R. D., Collins, G., Kirton, L., Snell, K. I., Ensor, J., Whittle, R., Dhiman, P., van Smeden, M., Liu, X., Alderman, J., Nirantharakumar, K., Manson-Whitton, J., Westwood, A. J., Cazier, J.-B., Moons, K. G. M., Martin, G. P., Sperrin, M., Denniston, A. K., Jr, F. E. H. & Archer, L., 13 Feb 2025, In: BMJ. 388, 10 p., e080749.Research output: Contribution to journal › Article › peer-review
Open AccessFile132 Downloads (Pure) -
Development and internal validation of prognostic models for event-free survival in newly diagnosed Ewing sarcoma patients based on routinely collected clinical characteristics from the European randomised controlled trial, EE2012
Kirton, L., Riley, R., Gaunt, P., Brennan, B. & Snell, K., 20 Dec 2024, In: BMJ Open. 14, 12, 6 p., e082941.Research output: Contribution to journal › Article › peer-review
Open AccessFile62 Downloads (Pure) -
Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial
Brennan, B., Kirton, L., Marec-Bérard, P., Gaspar, N., Laurence, V., Martín-Broto, J., Sastre, A., Gelderblom, H., Owens, C., Fenwick, N., Strauss, S., Moroz, V., Whelan, J. & Wheatley, K., 29 Oct 2022, In: The Lancet. 400, 10362, p. 1513-1521 9 p.Research output: Contribution to journal › Article › peer-review
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Rethinking outcomes and statistical analyses for paediatric cancer trials
Kirton, L. (Co-Investigator), Gatz, S. (Co-Investigator), Billingham, L. (Co-Investigator) & Gates, S. (Principal Investigator)
1/11/25 → 30/04/28
Project: Research
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Prognostic models in rare diseases: methodology development with application to Ewing sarcoma
Kirton, L. (Principal Investigator)
1/10/23 → 30/09/28
Project: Other Government Departments
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MonoGerm: A phase II trial of carboplatin or vinblastine monotherapy induction prior to radiotherapy for intracranial germinoma
Billingham, L. (Principal Investigator), Lawson, A. (Co-Investigator), Kirton, L. (Co-Investigator), Apps, J. (Co-Investigator) & Arvanitis, T. (Co-Investigator)
1/08/23 → 31/07/33
Project: Research
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International clinical research programme to improve outcomes in newly diagnosed Ewing Sarcoma - Trial 1 (INTER-EWING-1)
Kirton, L. (Co-Investigator), Gaunt, P. (Principal Investigator) & Millen, G. (Co-Investigator)
Bayer, Bone Cancer Research Trust, Japan Agency For Medical Research And Development, Grupo Espanol De Investigatcion en Sarcoma (GEIS), Cancer Research UK, Fight Kids Cancer, SIOP Europe
1/12/21 → 30/11/32
Project: Research
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rEECur: International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma
Gaunt, P. (Principal Investigator) & Kirton, L. (Researcher)
PFIZER LIMITED, Bone Cancer Research Trust, Cancer Research UK
1/10/19 → 30/09/29
Project: Research