Dr. Latika Gupta is a Consultant Rheumatologist at Royal Wolverhampton Hospitals NHS Trust (RWT) and Clinical Associate Professor at the University of Birmingham. She leads the myositis service and digital health pathways at RWT, and serves as a Francis Crick Institute visiting scientist.

With training in clinical and translational sciences, Dr. Gupta has extensive experience managing complex connective tissue diseases in adults and children, developed during her tenure as Assistant Professor at Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS) in Lucknow, India.

Featured in Lancet Rheumatology as an early career researcher, Dr. Gupta is recognized as both a thoughtful researcher and active contributor to myositis research.

• Undergraduate medical training: Manipal University (2003-08, graduated top of the class)
• Postgraduate training: MD (General Medicine, 2010-13), Lady Hardinge Medical College, Delhi University
• Specialty training in rheumatology, DM (Clinical Immunology and Rheumatology, 2013-17), Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
• MRCP (SCE Rheumatology), 2018
• MRCP UK, 2022

Dr. Gupta is a Consultant Rheumatologist at Royal Wolverhampton NHS Trust, leading the myositis service and digital health pathways. She holds a Clinical Associate Professor position at the University of Birmingham and serves as a visiting scientist at the Francis Crick Institute. Her research addresses critical gaps in inflammatory connective tissue diseases understanding through international collaboration and digital innovation. Featured in Lancet Rheumatology as an inspiring early career researcher, she is recognized for her contributions to myositis research. 

Trained in clinical and translational sciences, she has built comprehensive cohorts including a biorepository of over 300 adult and juvenile myositis patients with longitudinal follow-up, core set assessments, and autoantibody profiling. Her characterisation of inflammatory myopathies in Indian populations revealed previously unrecognised autoantibody profiles, including a 50% prevalence of anti-MDA5 antibodies associated with unique clinical manifestations in darker skin tones. She documented higher early mortality rates from atypical infections, including tuberculosis, and identified novel biomarkers of muscle strength and accelerated senescence.

Her EMBO fellowship at University of Bath advanced immunoprecipitation techniques for antibody research, generating local and international grants to investigate antibody reporting methodologies. Drawing from diverse international experiences, her work explores ethnic differences in outcomes research, particularly bone health, reproductive care, and infections in rheumatic conditions.

Recent work integrating large language models into rheumatology represents pioneering clinical AI applications, including automated MDAAT-VAS scoring with performance comparable to human evaluators. Her 2025 Lancet Rheumatology publication on responsible AI implementation demonstrates continued leadership in this emerging field. She leverages digital tools and social media to enable collaborative research and foster patient empowerment, working closely with patient research partners to integrate patient voice and patient-reported outcomes into meaningful research.

With 318 peer-reviewed publications, 4,518 citations, and an H-index of 32, her research spans clinical phenotyping, digital health innovation, and health equity.

Leadership and Impact

Dr. Gupta chairs the IMACS Telemedicine Special Interest Group and leads the EULAR Study Group on Social Media in Rheumatology. As career enhancement lead for IMACS, lead of APLAR Young Rheumatology Partnerships Committee and CHANGE consortium, she addresses global health equity in rheumatology. 

Currently contributing to EULAR vaccination guidelines and serving on editorial boards including Rheumatology, her work directly influences international clinical practice.

Dr. Gupta trained in India and retrained in England, gaining invaluable experience across diverse healthcare systems. Her scientific inquiry was shaped through international fellowships at University of Pennsylvania, Oxford, Melbourne, Sweden (Karolinska Institute), and Singapore, alongside Assistant Professorship (2018-2021) at a tertiary care centre with a high volume of complex RMDs.

Her career demonstrates how rigorous scientific inquiry, combined with global collaboration and technological innovation, can address fundamental challenges in rare disease care and health equity.

Dr. Gupta's research focuses on immunological phenotyping and precision medicine approaches for connective tissue diseases, ultimately improving therapeutic landscapes and clinical trial outcomes for rheumatic conditions. Her current work also explores holistic healthcare approaches including dietary interventions in inflammatory conditions.

Dr Gupta's current work includes the STREAM study (discordance in reporting outcomes) and PRESERVE consortium for precision medicine approaches in connective tissue diseases research. She is also a EULAR methodologist in training. 

Recent Positions, Scientific Appointments, and Honors