Joseph Wragg

2023

Intra-promoter switch of transcription initiation sites in proliferation signaling-dependent RNA metabolism

Wragg, J. W., White, P-L., Hadzhiev, Y., Wanigasooriya, K., Stodolna, A., Tee, L., Barros-Silva, J. D., Beggs, A. D. & Müller, F., Dec 2023, In: Nature Structural and Molecular Biology. 30, 12, p. 1970-1984 15 p.

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Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior

Wragg, J. & Müller, F., 27 Nov 2023, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

Research output: Contribution to journal › Article

2022

Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

Baranasic, D., Hörtenhuber, M., Balwierz, P. J., Zehnder, T., Mukarram, A. K., Nepal, C., Várnai, C., Hadzhiev, Y., Jimenez-Gonzalez, A., Li, N., Wragg, J., D’Orazio, F. M., Relic, D., Pachkov, M., Díaz, N., Hernández-Rodríguez, B., Chen, Z., Stoiber, M., Dong, M., Stevens, I., & 35 othersRoss, S. E., Eagle, A., Martin, R., Obasaju, O., Rastegar, S., McGarvey, A. C., Kopp, W., Chambers, E., Wang, D., Kim, H. R., Acemel, R. D., Naranjo, S., Łapiński, M., Chong, V., Mathavan, S., Peers, B., Sauka-Spengler, T., Vingron, M., Carninci, P., Ohler, U., Lacadie, S. A., Burgess, S. M., Winata, C., van Eeden, F., Vaquerizas, J. M., Gómez-Skarmeta, J. L., Onichtchouk, D., Brown, B. J., Bogdanovic, O., van Nimwegen, E., Westerfield, M., Wardle, F. C., Daub, C. O., Lenhard, B. & Müller, F., 4 Jul 2022, In: Nature Genetics. 54, 7, p. 1037-1050 14 p.

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1 Citation (Scopus)

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2020

Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

Nepal, C., Hadzhiev, Y., Balwierz, P., Tarifeño-Saldivia, E., Cardenas, R., Wragg, J. W., Suzuki, A-M., Carninci, P., Peers, B., Lenhard, B., Andersen, J. B. & Müller, F., 10 Jan 2020, In: Nature Communications. 11, 1, 168.

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6 Citations (Scopus)

187 Downloads (Pure)

Embryonic tissue differentiation is characterized by transitions in cell cycle dynamic-associated core promoter regulation

Wragg, J. W., Roos, L., Vucenovic, D., Cvetesic, N., Lenhard, B. & Müller, F., 4 Sept 2020, In: Nucleic Acids Research. 48, 15, p. 8374-8392 19 p.

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3 Citations (Scopus)

2019

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Hadzhiev, Y., Qureshi, H. K., Wheatley, L., Cooper, L., Jasiulewicz, A., Van Nguyen, H., Wragg, J. W., Poovathumkadavil, D., Conic, S., Bajan, S., Sik, A., Hutvàgner, G., Tora, L., Gambus, A., Fossey, J. S. & Müller, F., 11 Feb 2019, In: Nature Communications. 10, 1, p. 691 691.

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16 Citations (Scopus)

256 Downloads (Pure)

2017

Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth

Kershaw, R. M., Roberts, D., Wragg, J., Shaaban, A., Humphreys, E., Halsall, J., Price, L., Bicknell, R., Gaston, K. & Jayaraman, P., 12 Jun 2017, In: Oncogenesis. 6, 6, e346.

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Sunitinib treatment enhances metastasis of innately drug resistant breast tumors

Wragg, J., Heath, V. & Bicknell, R., Feb 2017, In: Cancer Research. 77, 4, p. 1008-1020

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6 Citations (Scopus)

423 Downloads (Pure)

2016

Glutamate Receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

Ferguson, H., Wragg, J., Ward, S., Heath, V., Ismail, T. & Bicknell, R., 12 May 2016, In: OncoTarget. 7, 15, p. 20440-20454

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5 Citations (Scopus)

176 Downloads (Pure)

MCAM and LAMA4 are highly enriched in tumor blood vessels of renal cell carcinoma and predict patient outcome

Wragg, J., Finnity, J., Anderson, J., Ferguson, H., Porfiri, E., Bhatt, R., Murray, P., Heath, V. & Bicknell, R., 15 Apr 2016, In: Cancer Research. 76, 8, p. 2314-2326 13 p.

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