John Wilkie

Research output

Research output per year 2001 2001 2005 2007 2008 2011 2014 2018

• 17 Article
• 1 Review article

Research output per year

Research output per year

Search results

• 2018

  Rationalisation of a mechanism for sensing single point variants in target DNA using anthracene-tagged base discriminating probes

  Duprey, J-L. H. A., Bassani, D. M., Hyde, E. I., Jonusauskas, G., Ludwig, C., Rodger, A., Spencer, N., Vyle, J. S., Wilkie, J., Zhao, Z-Y. & Tucker, J. H. R., 21 Sept 2018, In: Organic and Biomolecular Chemistry. 16, 35, p. 6576-6585 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • anthracene 100%
  • oligonucleotides 63%
  • deoxyribonucleic acid 62%
  • strands 48%
  • Oligonucleotide Probe 43%
  3 Citations (Scopus)

  169 Downloads (Pure)
• 2017

  BTN3A1 discriminates γδ T cell phosphoantigens from non-antigenic small molecules via a conformational sensor in its B30.2 domain

  Salim, M., Knowles, T. J., Baker, A. T., Davey, M. S., Jeeves, M., Sridhar, P., Wilkie, J., Willcox, C. R., Kadri, H., Taher, T. E., Vantourout, P., Hayday, A., Mehellou, Y., Mohammed, F. & Willcox, B. E., 14 Sept 2017, In: ACS chemical biology. 12, 10, p. 2631-2643 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phosphoantigen 100%
  • Butyrophilins 91%
  • B30.2-SPRY Domain 87%
  • T-Lymphocytes 31%
  • Molecule 17%
  34 Citations (Scopus)

  375 Downloads (Pure)
• 2016

  Single Site Discrimination of Cytosine, 5-Methylcytosine and 5-Hydroxymethylcytosine in Target DNA using Anthracene-Tagged Fluorescent Probes

  Duprey, J-L. H. A., Bullen, G. A., Zhao, Z-Y., Bassani, D. M., Peacock, A. F. A., Wilkie, J. & Tucker, J. H. R., 2016, In: ACS chemical biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • 5-hydroxymethylcytosine 100%
  • anthracene 95%
  • 5-Methylcytosine 93%
  • Cytosine 78%
  • Fluorescent Dyes 69%
  5 Citations (Scopus)

  248 Downloads (Pure)
• 2014

  De novo design of Ln(III) coiled coils for imaging applications

  Berwick, M. R., Lewis, D. J., Jones, A. W., Parslow, R. A., Dafforn, T. R., Cooper, H. J., Wilkie, J., Pikramenou, Z., Britton, M. M. & Peacock, A. F. A., 29 Jan 2014, In: Journal of the American Chemical Society. 136, 4, p. 1166-1169

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lanthanoid Series Elements 100%
  • Rare earth elements 87%
  • Coil 60%
  • Terbium 60%
  • Imaging techniques 48%
  40 Citations (Scopus)

  232 Downloads (Pure)

• NMR and molecular dynamics study of the size, shape, and composition of reverse micelles in a cetyltrimethylammonium bromide (CTAB)/n-hexane/pentanol/water microemulsion

  Mills, A. J., Wilkie, J. & Britton, M. M., 11 Sept 2014, In: The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 118, 36, p. 10767-75 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Micelles 100%
  • Microemulsions 99%
  • Hexane 90%
  • Nuclear magnetic resonance 79%
  • bromides 76%
  25 Citations (Scopus)

  775 Downloads (Pure)
• 2011

  Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors: discrimination between various base-pair mismatches

  Duprey, J-L., Bassani, DM., Hyde, E., Ludwig, C., Rodger, A., Vyle, JS., Wilkie, J., Zhao, ZY. & Tucker, J. H. R., 2011, In: Supramolecular Chemistry. 23, 3-4, p. 273-277 5 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Probe 100%
  • DNA Sequence 91%
  • Anthracene 86%
  • Oligonucleotide 77%
  • Fluorescence 50%
  4 Citations (Scopus)

• The effect of leaving group on mechanistic preference in phosphate monoester hydrolysis

  Kamerlin, SCL. & Wilkie, J., 1 Jan 2011, In: Organic and Biomolecular Chemistry. 9, 15, p. 5394-5406 13 p.

  Research output: Contribution to journal › Article

  • Phosphate Monoester 100%
  • hydrolysis 73%
  • phosphates 64%
  • Potential Energy Surface 61%
  • Hydrolysis 59%
  9 Citations (Scopus)
• 2010

  Magnetic resonance studies of a redox probe in a reverse sodium bis(2-ethylhexyl)sulfosuccinate/octane/water microemulsion

  Binks, D. A., Spencer, N., Wilkie, J. & Britton, M. M., 10 Sept 2010, In: The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 114, 39, p. 12558-12564 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Micelles 100%
  • Microemulsions 99%
  • Oxidation-Reduction 86%
  • octanes 85%
  • micelles 72%
  9 Citations (Scopus)
• 2009

  Mechanism of CB1954 reduction by Escherichia coli nitroreductase

  Christofferson, A. & Wilkie, J., 1 Apr 2009, In: Biochemical Society Transactions. 37, p. 413-418 6 p.

  Research output: Contribution to journal › Article

  • tretazicar 100%
  • Nitroreductases 87%
  • Escherichia coli 38%
  • Reduction 24%
  • Cytotoxic Agent 22%
  18 Citations (Scopus)
• 2008

  Anion complexation via C–H centerdot center dot X interactions using a palladacyclic receptor

  Bedford, R. B., Betham, M., Butts, C. P., Coles, S. J., Hursthouse, M. B., Noelle Scully, P., Tucker, J. H. R., Wilkie, J. & Willener, Y., 1 Jan 2008, In: Chemical Communications. 21, p. 2429-31 3 p.

  Research output: Contribution to journal › Article › peer-review

  • X ray crystallography 100%
  • Complexation 95%
  • Nuclear magnetic resonance spectroscopy 88%
  • Organometallics 87%
  • Negative ions 78%
  41 Citations (Scopus)

• Synthesis andex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes

  Jones, MA., Notta, JK., Cobbold, M., Palendira, M., Hislop, A., Wilkie, J. & Snaith, J., 1 Mar 2008, In: Journal of Peptide Science. 14, 3, p. 313-320 8 p.

  Research output: Contribution to journal › Article

  • Epitope 100%
  • Cytomegalovirus 97%
  • Epitopes 84%
  • HLA-A*02:01 antigen 74%
  • Peptides 62%
  3 Citations (Scopus)
• 2007

  Structures of the dI2dIII1 Complex of Proton-Translocating Transhydrogenase with Bound, Inactive analogues of NADH and NADPH reveal active site geometries

  Bhakta, T., Whitehead, SJ., Snaith, J., Dafforn, T., Wilkie, J., Rajesh, S., White, S. & Jackson, J., 20 Mar 2007, In: Biochemistry. 46, 11, p. 3304-3318 15 p.

  Research output: Contribution to journal › Article

  • 1,4,5,6-tetrahydronicotinamide adenine dinucleotide phosphate 100%
  • NADP 73%
  • NAD 69%
  • Protons 69%
  • Catalytic Domain 61%
  15 Citations (Scopus)

• The role of metal ions in phosphate ester hydrolysis

  Kamerlin, SCL. & Wilkie, J., 1 Jan 2007, In: Organic and Biomolecular Chemistry. 5, p. 2098-2108 11 p.

  Research output: Contribution to journal › Article

  • hydrolysis 100%
  • esters 99%
  • metal ions 93%
  • Esters 89%
  • phosphates 87%
  46 Citations (Scopus)
• 2005

  Design of potentially photorefractive liquid crystalline materials: Derivatives of 3,6-disubstituted carbazole

  Belloni, M., Kariuki, B., Manickam, M., Wilkie, J. & Preece, J., 6 Jul 2005, In: Crystal Growth and Design. 5, 4, p. 1443-1450 8 p.

  Research output: Contribution to journal › Article

  • carbazoles 100%
  • Liquid crystals 90%
  • Electrostatics 76%
  • Carbazole 75%
  • Crystalline materials 74%
  32 Citations (Scopus)
• 2001

  NMR studies and semi-empirical energy calculations for cyclic ADP-ribose

  Rutherford, T., Wilkie, J., Vu, CQ., Schnackerz, K., Jacobson, MK. & Gani, D., 1 Jan 2001, In: Nucleosides Nucleotides & Nucleic Acids. 20, 8, p. 1485-1495 11 p.

  Research output: Contribution to journal › Article

  • Cyclic ADP-Ribose 100%
  • Hydrogen Bonding 25%
  • Adenine 24%
  • Protons 21%
  • Phosphates 18%
  4 Citations (Scopus)

• The 6-hydroxy group of inositol 1-phosphate serves as an H-bond donor in its catalytic hydrolysis by inositol monophosphase: Design and solid-phase synthesis of mechanism based inhibitors

  Gani, D., Akhtar, M., Beaton, M., Miller, D., Pybus, R., Stones, D., Rutherford, T. & Wilkie, J., 1 Jan 2001, In: Medicinal Chemistry into the Millennium. p. 190-207 18 p.

  Research output: Contribution to journal › Article

• The x-ray crystal structures and computational analysis of NH...pi hydrogen bonded bana-shaped carbazole derivatives and thermal analysis of higher mesogenic homologues

  Belloni, M., Manickam, M., Ashton, P., Kariuki, B., Preece, J., Spencer, N. & Wilkie, J., 1 Oct 2001, In: Molecular Crystals and Liquid Crystals. 369, 1, p. 17-35 19 p.

  Research output: Contribution to journal › Article

  • carbazoles 100%
  • thermal analysis 68%
  • crystal structure 56%
  • hydrogen 43%
  • molecular orbitals 35%
  12 Citations (Scopus)