Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression
Almaghrabi, R., Alyahyawi, Y., Keane, P., Mian, S. A., Habel, K., Atkinson, A., Ward, C., Bayley, R., Sargas, C., Menendez, P., Murphy, G. J., Sobahy, T., Baghdadi, M. A., Flemban, A. F., Kabrah, S. M., Torres-Ruiz, R., Papapetrou, E. P., Akerman, I., Raghavan, M. & Barragan, E. & 3 others, , 1 Jul 2025, In: Nature Communications. 16, 1, 22 p., 5489.Research output: Contribution to journal › Article › peer-review
Open AccessFile60 Downloads (Pure) -
LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells
Cuozzo, F., Viloria, K., Shilleh, A. H., Nasteska, D., Frazer-Morris, C., Tong, J., Jiao, Z., Boufersaoui, A., Marzullo, B., Rosoff, D. B., Smith, H. R., Bonner, C., Kerr-Conte, J., Pattou, F., Nano, R., Piemonti, L., Johnson, P. R. V., Spiers, R., Roberts, J. & Lavery, G. G. & 13 others, , 23 Apr 2024, In: Cell Reports. 43, 4, 114047.Research output: Contribution to journal › Article › peer-review
Open AccessFile123 Downloads (Pure) -
Loss of Ezh2 function remodels the DNA replication initiation landscape
Prorok, P., Forouzanfar, F., Murugarren, N., Peiffer, I., Charton, R., Akerman, I. & Méchali, M., 25 Apr 2023, In: Cell Reports. 42, 4, 16 p., 112280.Research output: Contribution to journal › Article › peer-review
Open AccessFile91 Downloads (Pure) -
Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene
Akerman, I., Maestro, M. A., De Franco, E., Grau, V., Flanagan, S., Garcia-Hurtado, J., Mittler, G., Ravassard, P., Piemonti, L., Ellard, S., Hattersley, A. T. & Ferrer, J., 13 Apr 2021, In: Cell Reports. 35, 2, 108981.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)232 Downloads (Pure) -
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
Nasteska, D., Fine, N., Ashford, F., Cuozzo, F., Viloria, K., Smith, G., Dahir, A., Dawson, P. W. J., Lai, Y.-C., Bastidas-Ponce, A., Bakhti, M., Rutter, G., Fiancette, R., Nano, R., Piemonti, L., Lickert, H., Zhou, Q., Akerman, I. & Hodson, D., 29 Jan 2021, In: Nature Communications. 12, 1, 19 p., 674.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)275 Downloads (Pure)
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Decoding the 3-dimensional epigenomic landscape for human pancreas development and risk of type 2 diabetes mellitus
Akerman, I. (Principal Investigator)
1/11/25 → 31/12/26
Project: Research
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Developing autologous stem cell derived therapies for cystic fibrosis related diabetes
Akerman, I. (Principal Investigator)
29/09/25 → 30/09/28
Project: Research
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Leveraging GLP1R and GIPR as molecular addresses for precision beta cell therapy/regeneration during type 1 diabetes
Akerman, I. (Principal Investigator)
1/03/24 → 28/02/29
Project: Research
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BetaCell Birmingham - Infrastructure grant
Akerman, I. (Principal Investigator)
1/10/24 → 14/03/25
Project: Research Councils
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MRC IAA-1: Production of stem cell derived pancreatic beta cells for regenerative therapy for diabetes (BetaCell)
Akerman, I. (Principal Investigator) & Docherty, F. (Co-Investigator)
The Wellcome Trust, Medical Research Council
1/09/23 → 31/12/24
Project: Research Councils