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Ian Tomlinson

Prof

20052026

Research activity per year

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Evolutionary characterization of lung cancer metastasis

    TRACERx consortium, TRACERx EVO Consortium & PEACE Consortium, 21 May 2026, In: Nature. 653, p. 911–922 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    9 Downloads (Pure)

  • 82P Genomic alterations in biliary tract cancer and association with patient outcomes: Translational data from patients treated on the randomised phase III multicentre BILCAP clinical trial

    Crolley, V. E., Guest, R., Beggs, A. D., Jaynes, E., Thorn, S., Tomlinson, I., Valle, J. W., Primrose, J. N. & Bridgewater, J. A., 5 Nov 2025, In: Annals of Oncology. 36, Supplement 2, p. S234-S234 1 p.

    Research output: Contribution to journal › Abstract › peer-review

  • Comparison between germline and somatic loss-of-function RNF43 mutations reveals different genotype-phenotype associations and provides insights into the genetic mechanisms of colorectal tumourigenesis

    Palles, C., Freeman-Mills, L., Arbe-Barnes, E., Feeley, N., Chegwidden, L., Curley, H., Galavotti, S., Woolley, C., Cheadle, J., Mouradov, D., Sieber, O., Salatino, S., Thorn, S., Goel, A., Fernandez-Tajes, J., Omwenga, S., Biswas, S., Maughan, T., Leedham, S. J. & S:CORT Consortium & 8 others, UK Colorectal Cancer Genomics Consortium, Colorectal Tumour Gene Identification (CORGI) Consortium, WGS500 Consortium, Koelzer, V. H., Wang, L. M., Arnold, R., East, J. E. & Tomlinson, I., 24 Dec 2025, (E-pub ahead of print) In: Gut. 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    22 Downloads (Pure)

  • Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers

    Ward, J. C., Soriano, I., Thorn, S., Fernández-Tajes, J., Sherwood, K., Gül, G., Scheffers, J., Frangou, A., Kinnersley, B., Kafetzopoulos, I., Sproul, D., Galavotti, S., Palles, C., Gruber, A. J., Church, D. N. & Tomlinson, I., 25 Aug 2025, In: Genome medicine. 17, 1, 20 p., 95.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    25 Downloads (Pure)

  • Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

    Chen, Z., Guo, X., Tao, R., Huyghe, J. R., Law, P. J., Fernandez-Rozadilla, C., Ping, J., Jia, G., Long, J., Li, C., Shen, Q., Xie, Y., Timofeeva, M. N., Thomas, M., Schmit, S. L., Díez-Obrero, V., Devall, M., Moratalla-Navarro, F., Fernandez-Tajes, J. & Palles, C. & 185 others, Sherwood, K., Briggs, S. E. W., Svinti, V., Donnelly, K., Farrington, S. M., Blackmur, J., Vaughan-Shaw, P. G., Shu, X.-O., Lu, Y., Broderick, P., Studd, J., Harrison, T. A., Conti, D. V., Schumacher, F. R., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S.-S., Shin, M.-H., Shin, A., Ahn, Y.-O., Kim, D.-H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y.-T., Jia, W.-H., Hopper, J. L., Jenkins, M. A., Win, A. K., Pai, R. K., Figueiredo, J. C., Haile, R. W., Gallinger, S., Woods, M. O., Newcomb, P. A., Duggan, D., Cheadle, J. P., Kaplan, R., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, J.-P., Jousilahti, P., Knekt, P., Aaltonen, L. A., Rissanen, H., Pukkala, E., Eriksson, J. G., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Männistö, S., Albanes, D., Weinstein, S. J., Ruiz-Narvaez, E., Palmer, J. R., Buchanan, D. D., Platz, E. A., Visvanathan, K., Ulrich, C. M., Siegel, E., Brezina, S., Gsur, A., Campbell, P. T., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M. L., Potter, J. D., Tsilidis, K. K., Schulze, M. B., Gunter, M. J., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Bishop, D. T., Giles, G. G., Southey, M. C., Idos, G. E., McDonnell, K. J., Abu-Ful, Z., Greenson, J. K., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y.-R., Steinfelder, R., Keku, T. O., van Guelpen, B., Hudson, T. J., Hampel, H., Pearlman, R., Berndt, S. I., Hayes, R. B., Martinez, M. E., Thomas, S. S., Pharoah, P. D. P., Larsson, S. C., Yen, Y., Lenz, H.-J., White, E., Li, L., Doheny, K. F., Pugh, E., Shelford, T., Chan, A. T., Cruz-Correa, M., Lindblom, A., Hunter, D. J., Joshi, A. D., Schafmayer, C., Scacheri, P. C., Kundaje, A., Schoen, R. E., Hampe, J., Stadler, Z. K., Vodicka, P., Vodickova, L., Vymetalkova, V., Edlund, C. K., Gauderman, W. J., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S. J., van Duijnhoven, F., Feskens, E. J. M., Sakoda, L. C., Gago-Dominguez, M., Wolk, A., Pardini, B., FitzGerald, L. M., Lee, S. C., Ogino, S., Bien, S. A., Kooperberg, C., Li, C. I., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Yamaji, T., Sawada, N., Iwasaki, M., Le Marchand, L., Wu, A. H., Qu, C., McNeil, C. E., Coetzee, G., Hayward, C., Deary, I. J., Harris, S. E., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Lau, K. S., Zhao, H., Hsu, L., Cai, Q., Dunlop, M. G., Gruber, S. B., Houlston, R. S., Moreno, V., Casey, G., Peters, U., Tomlinson, I. & Zheng, W., 26 Apr 2024, In: Nature Communications. 15, 1, 17 p., 3557.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    111 Downloads (Pure)
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