Personal profile
Research interests
My research group focuses on how genome plasticity drives the co-evolution of host-pathogen interactions and the development of drug resistance.
Qualifications
- Postdoctroal Fellow, Johns Hopkin University School of Medicine, Baltimore, MD, USA
- PhD, University of Minnesota, Minneapolis, MN, USA
- BSc, National Taiwan University, Taipei, Taiwan
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Ultrasound-Responsive Nanoparticles Enable Hydrophobic Antibiotic Release and Deep Penetration for Biofilm Treatment
Odyniec, M. L., Bell, D. J., Gallant, B. M., Firdaus, R., Ball, G., Hughes, L., Oxtoby, R., Hewitt, B. J., Williams, C. M., Muguruza, A. R., Overton, T. W., Tsai, H.-J., Chiu, Y.-L., Kubicki, D. J., Walmsley, A. D., Kuehne, S. A. & Pikramenou, Z., 23 Mar 2026, In: JACS Au. 6, 3, p. 1847–1859 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Toll-1-dependent immune evasion induced by fungal infection leads to cell loss in the Drosophila brain
Singh, D. N. D., Roberts, A. R. E., Wang, X., Li, G., Quesada Moraga, E., Alliband, D., Ballou, E., Tsai, H.-J. & Hidalgo, A., 13 Feb 2025, In: PLoS Biology. 23, 2, e3003020.Research output: Contribution to journal › Article › peer-review
Open AccessFile106 Downloads (Pure) -
Quantifying the Mechanical Properties of Yeast Candida albicans Using Atomic Force Microscopy-based Force Spectroscopy
Jones, C. R., Zhang, Z. J. & Tsai, H. J., 6 May 2023, Antifungal Immunity: Methods and Protocols. Drummond, R. A. (ed.). 1 ed. Humana Press, p. 1-13 13 p. (Methods in Molecular Biology; vol. 2667).Research output: Chapter in Book/Report/Conference proceeding › Chapter
-
Estrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system
Kumwenda, P., Cottier, F., Hendry, A. C., Kneafsey, D., Keevan, B., Gallagher, H., Tsai, H. J. & Hall, R. A., 4 Jan 2022, In: Cell Reports. 38, 1, 11 p., 110183.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)99 Downloads (Pure) -
Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries
Credle, J. J., Gunn, J., Sangkhapreecha, P., Monaco, D. R., Zheng, X. A., Tsai, H. J., Wilbon, A., Morgenlander, W. R., Rastegar, A., Dong, Y., Jayaraman, S., Tosi, L., Parekkadan, B., Baer, A. N., Roederer, M., Bloch, E. M., Tobian, A. A. R., Zyskind, I., Silverberg, J. I. & Rosenberg, A. Z. & 4 others, , 19 Aug 2022, In: Nature Biomedical Engineering. 6, 8, p. 992-1003 12 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)
-
Starship transposons: Carriers of adaptive cargo across species boundaries in pathogenic fungi?
Tsai, H.-J. (Co-Investigator) & McDonald, M. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/01/24 → 30/04/26
Project: Research Councils
-
Investigating the pleiotropic effects of aneuploidy in antifungal resistance
Tsai, H.-J. (Principal Investigator)
THE ACADEMY OF MEDICAL SCIENCES
1/07/22 → 30/06/26
Project: Research
-
Enhancing fluconazole efficacy and precision through novel molecular and nanoscale approaches
Drummond, R. (Co-Investigator), Pikramenou, Z. (Co-Investigator), Tsai, H.-J. (Principal Investigator) & Cox, L. (Co-Investigator)
1/12/24 → 1/03/26
Project: Research
-
A pipeline for high-throughput microbial isolation, sorting, screening and synthetic community assembly
McDonald, M. (Co-Investigator), van Schaik, W. (Co-Investigator), McDonald, J. (Principal Investigator), Quick, J. (Co-Investigator), Overton, T. (Co-Investigator), Cox, M. (Co-Investigator), Jackson, R. (Co-Investigator), Crouch, L. (Co-Investigator), Tsai, H.-J. (Co-Investigator) & Blair, J. (Co-Investigator)
Biotechnology & Biological Sciences Research Council
1/08/23 → 31/07/24
Project: Research Councils
-
Targeting Novel Factors from the Host-Fungal Interface to Combat Antifungal Resistance
Tsai, H.-J. (Principal Investigator)
GILEAD SCIENCES INTERNATIONAL LTD
1/08/21 → 27/02/26
Project: Research
Activities
- 1 Editorial board of a journal
-
Frontiers in Microbiology (Journal)
Tsai, H.-J. (Editor)
2020Activity: Publication peer-review and editorial work › Editorial board of a journal