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Guy Pratt

Prof

Accepting PhD Students

PhD projects

Dr Pratt is keen to support and stimulate Haematology research. His main interests are as follows:

Multiple Myeloma
Chronic Lymphocytic Leukaemia
UK-wide genome association studies in CLL
The kinetics of serum-free light chains (FLC) as a rapid marker of response in multiple myeloma
The prognostic importance of serum FLC in chronic lymphocytic leukaemia and lymphoma

Guy is happy to supervise doctoral researchers both within Cancer Studies and in other collaborating groups at the University.

20012026

Research activity per year

Personal profile

Research interests

  • Examining the tumour microenvironment in multiple myeloma and the premalignant MGUS including identifying metabolic changes and the effects of hypoxia on T cells and stromal cells with the aim of developing target therapies (Dr Sarah Dimeloe, Professor Chris Bunce). 
  • The clinical utility of the mass spectrometry assay for measuring myeloma proteins in a range plasma cell disorders as a marker of disease and minimal residual disease (Binding Site UK Ltd, Birmingham, UK) (Dr Hannah Giles, Professor Ashu Wechalekar).
  • Understanding immunity to common infections and responses to vaccination in patients with plasma cell disorders and CLL
  • Detection of myeloma proteins and assessment of immunity in saliva in patients with plasma cell disorders (Professor Iain Chapple, Professor Mark Drayson).
  • Understanding the metabolic changes in the transformation from MGUS to multiple myeloma (Professor Chris Bunce, Professor Mark Drayon, Dr Sarah Dimeloe, Professor Dan Tennant).
  • Collaborations providing real world data for patients with myeloma, amyloidosis and Waldenstroms (UK wide looking at outcomes for patient groups and the impact of treatments).
  • Development of a specialised tertiary centre for patients AL amyloidosis and monoclonal gammopathy of clinical significance (Dr Jenny Pinney, Dr Will Moody, Professor Yusuf Rajabally).

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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Collaborations and top research areas from the last five years

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