Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Gary Middleton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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14P Towards targeting the true driver within the 3q26-29 amplicon
Robbins, H. L., Finch, A., Tee, L., Beggs, A. D. & Middleton, G., 5 Nov 2025, (E-pub ahead of print) In: Annals of Oncology. 36, p. S213 1 p.Research output: Contribution to journal › Abstract › peer-review
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1515MO Clinical outcomes and PD-L1 expression analyses from a trial of mRNA-4359 plus pembrolizumab in checkpoint inhibitor-resistant/refractory (CPI-R/R) melanoma
Pinato, D. J., Sullivan, R. J., Khattak, A., Sarker, D., Medina, T., Karydis, I., Middleton, G., Spiliopoulou, P., Rohatgi, A., Gutierrez, M., Daud, A. I., Boni, V., Middleton, M. R., Sweis, R., Bauman, J. E., Mao, X., Daghestani, H., Abadier, M., Barlaskar, F. & Long, G. V., 5 Nov 2025, In: Annals of Oncology. 36, Supplement 2, p. S908-S909 2 p.Research output: Contribution to journal › Abstract › peer-review
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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
Middleton, G., Robbins, H. L., Fletcher, P., Savage, J., Mehmi, M., Summers, Y., Greystoke, A., Steele, N., Popat, S., Jain, P., Spicer, J., Cave, J., Shaw, P., Gilligan, D., Power, D., Fennell, D., Bajracharya, M., Mcbride, D. J., Maheswari, U. & Frankell, A. M. & 3 others, , 11 Mar 2025, In: npj Precision Oncology. 9, 1, 11 p., 67.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Downloads (Pure) -
Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology
Phillips, R., Basu, B., Butt, Z., Beloueche, M., Cook, N., Crabb, S. J., Greystoke, A., Hargrave, D., Jones, R., Kureeman, M. Y., Lopez, J., McKeeve, C., Meissner, M., O'Carrigan, B., Parkes, E. E., Ronghe, M., Roxburgh, P., Sarker, D., Savage, K. I. & Shaw, P. H. S. & 7 others, , 8 Nov 2025, (E-pub ahead of print) In: British Journal of Cancer. 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Final results of ANICCA-Class II, a single arm, open-label phase II trial assessing nivolumab in tissue-specific class II expressing metastatic microsatellite stable colorectal cancer, with a parallel assessment of the immunoscore-immune checkpoint as a predictive biomarker for single-agent anti-PD-1
Middleton, G., Gaskell, C., Savage, J., Bridgewater, J., Ross, P., Saunders, M., Palmer, D., Plummer, R., Clive, S., Coyle, V., Thomas, A., Cunningham, D., Taniere, P. & Billingham, L., 17 Dec 2025, In: Journal for ImmunoTherapy of Cancer. 13, 12, 13 p., e012749.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure)
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A translational programme for DETERMINE (Determining Extended Therapeutic Indications for Existing drugs in Rare Molecularly-defined Indications using a National Evaluation platform trial)
Beggs, A. (Co-Investigator) & Middleton, G. (Principal Investigator)
1/06/25 → 30/11/27
Project: Research
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Thrombo-STOP: Apixaban thromboprophylaxis to prevent venous thromboembolism in ambulatory lung cancer patients undergoing systemic anticancer treatment
Jowett, S. (Co-Investigator), Billingham, L. (Co-Investigator), Ignatowicz, A. (Co-Investigator), Newnham, M. (Principal Investigator), Turner, A. (Co-Investigator), Pirrie, S. (Co-Investigator) & Middleton, G. (Co-Investigator)
1/03/25 → 28/02/30
Project: Other Government Departments
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CRC-STARS: Colorectal cancer - Stratification of Therapies through Adaptive Responses
Beggs, A. (Principal Investigator) & Middleton, G. (Co-Investigator)
1/01/25 → 31/12/29
Project: Research
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CRUK CRCTU Core Funding
Fisher, B. (Co-Investigator), Billingham, L. (Researcher), Bach, S. (Researcher), Kearns, P. (Co-Investigator), Pratt, G. (Researcher), Bowden, S. (Principal Investigator), Rea, D. (Researcher), Middleton, G. (Co-Investigator) & Gates, S. (Researcher)
1/10/23 → 30/09/28
Project: Research
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Investigating Regulatory B cells as determinants of immune-related adverse events following checkpoint blockade therapy
Middleton, G. (Co-Investigator) & Patel, A. (Principal Investigator)
1/08/23 → 31/07/26
Project: Research
Activities
- 3 Conference, workshop or symposium
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A Phase II Clinical Trial with Efficacy and Toxicity Outcomes and Baseline Covariates
Brock, K. (Speaker), Billingham, L. (Contributor), Middleton, G. (Contributor) & Yap, C. (Contributor)
2 Jul 2018Activity: Academic and Industrial events › Conference, workshop or symposium
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Using a Bayesian adaptive phase II trial design to test multiple genetic-marker-directed drugs in the National Lung Matrix Trial
Billingham, L. (Invited speaker), Brock, K. (Invited speaker), Llewellyn, L. (Invited speaker), Popat, S. (Invited speaker) & Middleton, G. (Invited speaker)
6 Sept 2015 → 9 Sept 2015Activity: Academic and Industrial events › Conference, workshop or symposium
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Design dilemmas in the multi-drug, genetic-marker-directed, non-comparative, multi-centre, multi-arm phase II National Lung Matrix Trial
Billingham, L. (Invited speaker), Llewellyn, L. (Invited speaker), Brock, K. (Invited speaker), Popat, S. (Invited speaker) & Middleton, G. (Invited speaker)
26 Aug 2014Activity: Academic and Industrial events › Conference, workshop or symposium