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Ben Cardoen

Dr.

20162025

Research activity per year

Personal profile

Research interests

I focus on designing scalable, interpretable algorithms to enable novel scientific discovery from biomedical imaging data at multiple scales ranging from diffuse optical tomography (DOT) to confocal and superresolution microscopy (SRM, STED, SMLM, dSTORM). I leverage and extend concepts from several fields: fuzzy computing (belief theory, information fusion) to simulation (discrete event simulators, agent based simulation), graph algorithms, vector fields, recurrent neural networks, and structural causal discovery from complex data. 
Application domains range from degenerative (Alzheimer, ageing) to metabolic (diabetes) and infectious disease, with a specific focus on elucidating subcellular function from complex data. Whenever possible I like to design algorithms that push beyond the empirical resolution limits of modalities and that are adaptive or robust to complex noise models.

Biography

I started my research career developing a paralell discrete event simulator in C++ with the capability to switch at runtime between simulation paradigms enabling simulation designers to find automatic optima for their domain uses. In my Master's I combined distributed metaheuristics with hyperheuristics to enable symbolic regression for complex epidemiological simulations. 
 My doctorate focused on designing algorithms that extract interactions below observable empirical precision from superresolution microscopy. 
In my postdoctoral fellowship I work on inferring equilibria from causal topological signatures in noisy biomedical imaging modalities.

Education/Academic qualification

Doctor of Science, Computational Reconstruction of Multiscale Interaction in Multichannel Superresolution Microscopy, Simon Fraser University

1 Sept 201730 Apr 2024

Award Date: 24 Apr 2024

Master in Science, Convergence of Symbolic Regression Using Metaheuristics (Computer Science), University of Antwerp

1 Sept 201530 Jun 2017

Award Date: 30 Jun 2017

Bachelor of Science, A Parallel Discrete Event Simulator in C++ (Computer Science), University of Antwerp

1 Sept 201230 Jun 2015

Award Date: 30 Jun 2015

Keywords

  • QA75 Electronic computers. Computer science
  • machine learning
  • Image processing
  • reconstruction
  • uncertainty
  • scalability
  • vector fields
  • graph algorithms
  • QA76 Computer software
  • simulation
  • prediction
  • RB Pathology
  • Ageing
  • Degenerative disease
  • Mitochondria
  • Protein Structure

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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