Research output per year
Research output per year
- 34 results
Search results
-
1989
A study of red cell membrane properties in relation to malarial invasion
Rangachari, K., Beaven, G. H., Nash, G. B., Clough, B., Dluzewski, A. R., Myint-Oo, Wilson, R. J. M. & Gratzer, W. B., Apr 1989, In: Molecular and biochemical parasitology. 34, 1, p. 63-74 12 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
1992
Basis of unique red cell membrane properties in hereditary ovalocytosis
Schofield, A. E., Tanner, M. J. A., Pinder, J. C., Clough, B., Bayley, P. M., Nash, G. B., Dluzewski, A. R., Reardon, D. M., Cox, T. M., Wilson, R. J. M. & Gratzer, W. B., 20 Feb 1992, In: Journal of Molecular Biology. 223, 4, p. 949-958 10 p.Research output: Contribution to journal › Article › peer-review
96 Citations (Scopus) -
Malaria and the red cell membrane
Pasvol, G., Clough, B. & Carlsson, J., Dec 1992, In: Blood Reviews. 6, 4, p. 183-192 10 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
1993
9 The red cell membrane and invasion by malarial parasites
Pasvol, G., Carlsson, J. & Clough, B., Jun 1993, In: Bailliere's Clinical Haematology. 6, 2, p. 513-534 22 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Actin in the merozoite of the malaria parasite, Plasmodium falciparum
Field, S. J., Pinder, J. C., Clough, B., Dluzewski, A. R., Wilson, R. J. M. & Gratzer, W. B., 1993, In: Cell Motility and the Cytoskeleton. 25, 1, p. 43-48 6 p.Research output: Contribution to journal › Article › peer-review
69 Citations (Scopus) -
1995
Mechanism of regulation of malarial invasion by extraerythrocytic ligands
Clough, B., Paulitschke, M., Nash, G. B., Bayley, P. M., Anstee, D. J., Wilson, R. J. M., Pasvol, G. & Gratzer, W. B., Jan 1995, In: Molecular and biochemical parasitology. 69, 1, p. 19-27 9 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
1996
Plasmodium falciparum lacks sialidase and trans-sialidase activity
Clough, B., Atilola, F. A., Healy, N., Pereira, M. E. A., Bethell, R. C., Penn, C. R. & Pasvol, G., 1996, In: Parasitology. 112, 5, p. 443-449 7 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
1997
Thiostrepton binds to malarial plastid rRNA
Clough, B., Strath, M., Preiser, P., Denny, P. & Wilson, 7 Apr 1997, In: FEBS Letters. 406, 1-2, p. 123-125 3 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
1998
A subtilisin-like protein in secretory organelles of Plasmodium falciparum merozoites
Blackman, M. J., Fujioka, H., Stafford, W. H. L., Sajid, M., Clough, B., Fleckt, S. L., Aikawa, M., Grainger, M. & Hackett, F., 4 Sept 1998, In: Journal of Biological Chemistry. 273, 36, p. 23398-23409 12 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Citations (Scopus) -
Plasmodium falciparum: The importance of IgM in the resetting of parasite-infected erythrocytes
Clough, B., Atilola, F. A., Black, J. & Pasvol, G., May 1998, In: Experimental Parasitology. 89, 1, p. 129-132 4 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
The role of rosetting in the multiplication of Plasmodium falciparum: Rosette formation neither enhances nor targets parasite invasion into uninfected red cells
Clough, B., Atilola, F. A. & Pasvol, G., 1998, In: British Journal of Haematology. 100, 1, p. 99-104 6 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
1999
Antibiotic inhibitors of organellar protein synthesis in Plasmodium falciparum
Clough, B., Rangachari, K., Strath, M., Preiser, P. R. & Wilson, R. J. M., Aug 1999, In: Protist. 150, 2, p. 189-195 7 p.Research output: Contribution to journal › Article › peer-review
67 Citations (Scopus) -
Meeting report: Molecular Parasitology, Woods Hole, USA, September 13-17, 1998.
Blackman, MJ. & Clough, B., Mar 1999, In: Protist.Research output: Contribution to journal › Article
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2001
Nifs and Sufs in malaria
Ellis, K. E. S., Clough, B., Saldanha, J. W. & Wilson, R. J. M., 2001, In: Molecular Microbiology. 41, 5, p. 973-981 9 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Citations (Scopus) -
2004
Enzymes for heme biosynthesis are found in both the mitochondrion and plastid of the malaria parasite Plasmodium falciparum
Sato, S., Clough, B., Coates, L. & Wilson, R. J. M., Mar 2004, In: Protist. 155, 1, p. 117-125 9 p.Research output: Contribution to journal › Article › peer-review
117 Citations (Scopus) -
2008
Hydrodynamic characterization of the SufBC and SufCD complexes and their interaction with fluorescent adenosine nucleotides
Petrovic, A., Davis, C. T., Rangachari, K., Clough, B., Wilson, R. J. M. & Eccleston, J. F., Jul 2008, In: Protein Science. 17, 7, p. 1264-1274 11 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
2013
Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication
Niedelman, W., Sprokholt, J. K., Clough, B., Frickel, E. M. & Saeij, J. P. J., Dec 2013, In: Infection and Immunity. 81, 12, p. 4341-4349 9 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Citations (Scopus) -
Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues
Large, J. M., Osborne, S. A., Smiljanic-Hurley, E., Ansell, K. H., Jones, H. M., Taylor, D. L., Clough, B., Green, J. L. & Holder, A. A., 1 Nov 2013, In: Bioorganic and Medicinal Chemistry Letters. 23, 21, p. 6019-6024 6 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (Scopus) -
Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)
Chapman, T. M., Osborne, S. A., Bouloc, N., Large, J. M., Wallace, C., Birchall, K., Ansell, K. H., Jones, H. M., Taylor, D., Clough, B., Green, J. L. & Holder, A. A., 15 May 2013, In: Bioorganic and Medicinal Chemistry Letters. 23, 10, p. 3064-3069 6 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Citations (Scopus) -
2014
Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1
Anseil, K. H., Jones, H. M., Whalley, D., Hearn, A., Taylor, D. L., Patin, E. C., Chapman, T. M., Osborne, S. A., Wallace, C., Birchall, K., Large, J., Bouloc, N., Smiljanic-Hurley, E., Clough, B., Moon, R. W., Green, J. L. & Holder, A. A., 1 Oct 2014, In: Antimicrobial Agents and Chemotherapy. 58, 10, p. 6032-6043 12 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Optimization of an imidazopyridazine series of inhibitors of plasmodium falciparum calcium-dependent protein kinase 1 (Pf CDPK1)
Chapman, T. M., Osborne, S. A., Wallace, C., Birchall, K., Bouloc, N., Jones, H. M., Ansell, K. H., Taylor, D. L., Clough, B., Green, J. L. & Holder, A. A., 24 Apr 2014, In: Journal of Medicinal Chemistry. 57, 8, p. 3570-3587 18 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Citations (Scopus) -
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
Wright, M. H., Clough, B., Rackham, M. D., Rangachari, K., Brannigan, J. A., Grainger, M., Moss, D. K., Bottrill, A. R., Heal, W. P., Broncel, M., Serwa, R. A., Brady, D., Mann, D. J., Leatherbarrow, R. J., Tewari, R., Wilkinson, A. J., Holder, A. A. & Tate, E. W., Feb 2014, In: Nature Chemistry. 6, 2, p. 112-121 10 p.Research output: Contribution to journal › Article › peer-review
165 Citations (Scopus) -
2016
Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii
Johnston, A. C., Piro, A., Clough, B., Siew, M., Virreira Winter, S., Coers, J. & Frickel, E. M., Aug 2016, In: Cellular Microbiology. 18, 8, p. 1056-1064 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Citations (Scopus)134 Downloads (Pure) -
K63-linked ubiquitination targets Toxoplasma gondii for endo-lysosomal destruction in IFNγ-stimulated human cells
Clough, B., Wright, J. D., Pereira, P. M., Hirst, E. M., Johnston, A. C., Henriques, R. & Frickel, E. M., 22 Nov 2016, In: PLoS pathogens. 12, 11, 25 p., e1006027.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)87 Downloads (Pure) -
2017
TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
Foltz, C., Napolitano, A., Khan, R., Clough, B., Hirst, E. M. & Frickel, E. M., 1 Dec 2017, In: Scientific Reports. 7, 1, 5209.Research output: Contribution to journal › Article › peer-review
Open Access45 Citations (Scopus) -
2019
C57BL/6 and 129 inbred mouse strains differ in gbp2 and gbp2b expression in response to inflammatory stimuli in vivo [version 1; peer review: 2 approved]
Clough, B., Finethy, R., Khan, R. T., Fisch, D., Jordan, S., Patel, H., Coers, J. & Frickel, E. M., 2019, In: Wellcome Open Research. 4, 124.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Defining host–pathogen interactions employing an artificial intelligence workflow
Fisch, D., Yakimovich, A., Clough, B., Wright, J., Bunyan, M., Howell, M., Mercer, J. & Frickel, E., 12 Feb 2019, In: eLife. 8, e40560.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)125 Downloads (Pure) -
Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis
Fisch, D., Bando, H., Clough, B., Hornung, V., Yamamoto, M., Shenoy, A. R. & Frickel, E. M., 1 Jul 2019, In: The EMBO journal. 38, 13, 19 p., e100926.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Citations (Scopus)232 Downloads (Pure) -
Human immunity to Toxoplasma gondii
Fisch, D., Clough, B. & Frickel, E. M., 2019, In: PLoS Pathogens. 15, 12, e1008097.Research output: Contribution to journal › Article › peer-review
Open Access38 Citations (Scopus) -
2020
Human GBP1 differentially targets salmonella and toxoplasma to license recognition of microbial ligands and caspase-mediated death
Fisch, D., Clough, B., Domart, M-C., Encheva, V., Bando, H., Snijders, A. P., Collinson, L. M., Yamamoto, M., Shenoy, A. R. & Frickel, E-M., 11 Aug 2020, In: Cell Reports. 32, 6, 108008.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)273 Downloads (Pure) -
Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection
Yakimovich, A., Huttunen, M., Samolej, J., Clough, B., Yoshida, N., Mostowy, S., Frickel, E-M. & Mercer, J., 9 Sept 2020, In: mSphere. 5, 5Research output: Contribution to journal › Article › peer-review
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2021
HRMAn 2.0: Next-generation artificial intelligence-driven analysis for broad host-pathogen interactions
Fisch, D., Evans, R., Clough, B., Byrne, S. K., Channell, W. M., Dockterman, J. & Frickel, E-M., Jul 2021, In: Cellular Microbiology. 23, 7, p. e13349 e13349.Research output: Contribution to journal › Article › peer-review
Open AccessFile255 Downloads (Pure) -
2022
Toxoplasma-proximal and distal control by GBPs in human macrophages
Fisch, D., Clough, B., Khan, R., Healy, L. & Frickel, E-M., 7 Jan 2022, In: Pathogens and disease. 79, 9, ftab058.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Downloads (Pure) -
2023
PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection
Fisch, D., Pfleiderer, M. M., Anastasakou, E., Mackie, G. M., Wendt, F., Liu, X., Clough, B., Lara-Reyna, S., Encheva, V., Snijders, A. P., Bando, H., Yamamoto, M., Beggs, A. D., Mercer, J., Shenoy, A. R., Wollscheid, B., Maslowski, K. M., Galej, W. P. & Frickel, E-M., 6 Oct 2023, In: Science. 382, 6666, 15 p., eadg2253.Research output: Contribution to journal › Article › peer-review