Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Navitoclax acts synergistically with irradiation to induce apoptosis in preclinical models of H3K27M-altered diffuse midline glioma
Vardon, A., Haston, S., Hamdi, H., Cooksley, G., Guiho, R., Carvalho, D., Carter, R., Boult, J. K. R., Gharai, D., Cloete, I., Grey, J., Apps, J., Zhou, D., Zheng, G., Martínez-Máñez, R., Lythgoe, M. F., Donovan, L. K., Carcaboso, A. M., Williams, O. & Hong, Y. & 7 others, , 29 Dec 2025, In: Scientific Reports. 15, 1, 15 p., 45094.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment
Panetti, S., McJannett, N. J., Fultang, L., Booth, S., Gneo, L., Scarpa, U., Smith, C., Vardon, A., Vettore, L., Whalley, C., Pan, Y., Varnai, C., Endou, H., Barlow, J., Tennant, D. A., Beggs, A. D., Mussai, F. J. & Santo, C. D., 9 May 2023, In: Blood Advances. 7, 9, p. 1754-1761 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Downloads (Pure) -
Risk of second brain tumour after radiotherapy for pituitary adenoma or craniopharyngioma: a retrospective, multicentre, cohort study of 3,679 patients with long-term imaging surveillance
Hamblin, R., Vardon, A., Akpalu, J., Tampourlou, M., Spiliotis, I., Sbardella, E., Lynch, J., Shankaran, V., Mavilakandy, A., Gagliardi, I., Meade, S., Hobbs, C., Cameron, A., Levy, M. J., Ayuk, J., Grossman, A., Ambrosio, M. R., Zatelli, M. C., Reddy, N. & Bradley, K. & 3 others, , 19 Jul 2022, In: The Lancet Diabetes and Endocrinology. 10, 8, p. 581-588 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile137 Downloads (Pure) -
Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma
Fultang, L., Gamble, L. D., Gneo, L., Berry, A. M., Egan, S. A., De Bie, F., Yogev, O., Eden, G. L., Booth, S., Brownhill, S., Vardon, A., McConville, C. M., Cheng, P. N., Norris, M. D., Etchevers, H. C., Murray, J., Ziegler, D. S., Chesler, L., Schmidt, R. & Burchill, S. A. & 3 others, , 13 Dec 2018, (E-pub ahead of print) In: Cancer Research.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)220 Downloads (Pure) -
The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100
De Santo, C., Booth, S., Vardon, A., Cousins, A., Tubb, V., Perry, T., Noyvert, B., Beggs, A., Ng, M., Halsey, C., Kearns, P., Cheng, P. & Mussai, F., 1 Apr 2018, In: International Journal of Cancer. 142, 7, p. 1490-1502 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)308 Downloads (Pure)
Projects
- 5 Active
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Targeting paediatric diffuse midline glioma using cell therapy
Vardon, A. (Principal Investigator)
1/04/26 → 31/03/27
Project: Research
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Exploiting the potential of protons and high-LET radiation in diffuse midline glioma
Vardon, A. (Co-Investigator) & Parsons, J. (Principal Investigator)
29/09/25 → 30/09/28
Project: Research
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Targeting Radiation-Induced Senescence in DMG: Identification of Novel Cell surface markers
Vardon, A. (Principal Investigator) & De Santo, C. (Co-Investigator)
1/09/25 → 31/08/27
Project: Research
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CAR BH3 DMG: Combining GD2 CAR T Cells With BH3 Mimetic In Diffuse Midline Glioma
Vardon, A. (Principal Investigator) & De Santo, C. (Co-Investigator)
THE ACADEMY OF MEDICAL SCIENCES
1/09/25 → 31/08/27
Project: Research
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BBSRC IAA (2024-26): A polypeptide-based safety-sort switch for advancing adoptive cell engineered
Vardon, A. (Principal Investigator)
Biotechnology & Biological Sciences Research Council
1/06/25 → 30/06/26
Project: Research Councils