Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A titin truncating variant linked to atrial fibrillation increases atrial profibrotic signalling and cholinergic sensitivity
Cumberland, M. J., Dasí, A., Sontayananon, N., Marcus, A., Qin, A., Riebel, L., Euchner, J., Azad, A. J., Hall, C., O'Shea, C., Smith, J. G., Papadopoulou, C., Miska, E. A., Pavlovic, D., Patrick, E., Chong, J., Kirchhof, P., Denning, C., Davies, B. & Rodriguez, B. & 2 others, , 27 May 2026, (E-pub ahead of print) In: Cardiovascular Research. cvag112.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure) -
Early Atrial Remodeling Drives Arrhythmia in Fabry Disease
Roy, A., O'Shea, C., Dasí, A., Patel, L., Cumberland, M. J., Nieves, D., Canagarajah, H., Thompson, S., Azad, A., Price, A., Hall, C., Alvior, A. M., Rath, P., Davies, B., Rodriguez, B., Holmes, A. P., Pavlovic, D., Townend, J. N., Geberhiwot, T. & Gehmlich, K. & 1 others, , 25 Jun 2025, (E-pub ahead of print) In: Circulation Arrhythmia and Electrophysiology. e013352.Research output: Contribution to journal › Article › peer-review
Open AccessFile94 Downloads (Pure) -
Targeting ecto‐5′‐nucleotidase (CD73) and cAMP alleviates carotid body hyperactivity and reduces blood pressure in chronically hypoxic rats
Nathanael, D., Coney, A. M., Alotaibi, D., Kumar, P. & Holmes, A. P., 16 Nov 2025, (E-pub ahead of print) In: The Journal of Physiology. 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Arrhythmogenesis in Fabry Disease
Roy, A., Cumberland, M., O'Shea, C., Holmes, A., Kalla, M., Gehmlich, K., Geberhiwot, T. & Steeds, R., 12 Apr 2024, (E-pub ahead of print) In: Current cardiology reports.Research output: Contribution to journal › Article › peer-review
Open AccessFile91 Downloads (Pure) -
Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue model [version 1; peer review: 1 approved, 2 approved with reservations]
Cumberland, M., Euchner, J., Azad, A., Vo, N. T. N., Kirchhof, P., Holmes, A., Denning, C. & Gehmlich, K., 30 Jan 2024, In: F1000Research. 12, 22 p., 1224.Research output: Contribution to journal › Article › peer-review
Open AccessFile522 Downloads (Pure)
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Identifying a new role for the carotid body in mediating cardiovascular reflex responses to heat stress
Holmes, A. (Principal Investigator), Pavlovic, D. (Researcher), Gehmlich, K. (Co-Investigator), Coney, A. (Co-Investigator) & O'Shea, C. (Researcher)
1/09/25 → 31/08/27
Project: Research
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How to make sense of cardiomyopathy-associated filamin C missense variants? Disease mechanisms and treatment options for the test case variant Filamin C M82K
Gehmlich, K. (Principal Investigator), Pavlovic, D. (Co-Investigator), O'Shea, C. (Co-Investigator) & Holmes, A. (Co-Investigator)
1/05/25 → 30/04/27
Project: Research
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Inflammatory signalling in the left atrium, noradrenaline transporter and atrial fibrillation in animal models of obstructive sleep apnoea [Sub-award of 1001749]
Coney, A. (Co-Investigator), Holmes, A. (Principal Investigator) & Brain, K. (Co-Investigator)
Kennedy Trust For Rheumatology Research
1/06/22 → 31/05/25
Project: Research
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Investigating the mechanisms of succinate mediated Nav1.5 dysfunction in human cardiac cell models Sub-project of 21502
Gehmlich, K. (Co-Investigator) & Holmes, A. (Principal Investigator)
1/05/22 → 30/04/23
Project: Research
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Defining the mechanistic importance of CD73 in promoting carotid body-mediated hypertension and cardiac arrhythmia in response to pathological hypoxia
Coney, A. (Co-Investigator), Holmes, A. (Principal Investigator) & Kumar, P. (Co-Investigator)
1/10/21 → 30/09/24
Project: Research
Prizes
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British Society for Cardiovascular Research and British Atherosclerosis Society Young Investigator Award Winner (2015)
Holmes, A. (Recipient), Jun 2015
Prize: Prize (including medals and awards)
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Editorial Fellow of the Journal of Physiology
Holmes, A. (Recipient), 2020
Prize: Fellowship awarded competitively
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Postdoctoral / Early Career Researcher Career Development And Training (PERCAT) Teaching and Mentoring Award Winner (2017)
Holmes, A. (Recipient), Jun 2017
Prize: Prize (including medals and awards)
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University of Birmingham Postgraduate A.E. Hills Scholarship (2012)
Holmes, A. (Recipient), 2012
Prize: Prize (including medals and awards)
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University of Birmingham Postgraduate A.E. Hills Scholarship (2013)
Holmes, A. (Recipient), 2013
Prize: Prize (including medals and awards)