Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Alexandre Slater is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Affimer reagents as tool molecules to modulate platelet GPVI-ligand interactions and specifically bind GPVI dimer
Xu, R.-G., Tiede, C., Calabrese, A. N., Cheah, L. T., Adams, T. L., Gauer, J. S., Hindle, M. S., Webb, B. A., Yates, D. M., Slater, A., Duval, C., Naseem, K. M., Herr, A. B., Tomlinson, D. C., Watson, S. P. & Ariëns, R. A. S., 13 Aug 2024, In: Blood Advances. 8, 15, p. 3917-3928 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Downloads (Pure) -
GPVI inhibition: Advancing antithrombotic therapy in cardiovascular disease
Slater, A., Khattak, S. & Thomas, M. R., 7 Mar 2024, (E-pub ahead of print) In: European heart journal. Cardiovascular pharmacotherapy. 9 p., pvae018.Research output: Contribution to journal › Article › peer-review
Open AccessFile90 Downloads (Pure) -
Purification and characterisation of the platelet-activating GPVI/FcRγ complex in SMALPs
Wang, X., Slater, A., Lee, S. C., Harrison, N., Pollock, N. L., Bakker, S. E., Navarro, S., Nieswandt, B., Dafforn, T. R., García, Á., Watson, S. P. & Tomlinson, M. G., 1 Apr 2024, In: Archives of Biochemistry and Biophysics. 754, 109944.Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Downloads (Pure) -
Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2 and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand
Martin, E., Clark, J., Montague, S., Moran, L. A., Di, Y., Bull, L. J., Whittle, L., Raka, F., Buka, R., Zafar, I., Kardeby, C., Slater, A. & Watson, S., 1 Jan 2024, In: Journal of Thrombosis and Haemostasis. 22, 1, p. 271-285Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Downloads (Pure) -
Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy JTH
Alenazy, F., Harbi, M., Kavanagh, D., Price, J., Brady, P., Hargreaves, O., Harrison, P., Slater, A., Tiwari, A., Nicolson, P., Connolly, D., Kirchhof, P., Kalia, N., Jandrot-Perrus, M., Mangin, P. H., Watson, S. & Thomas, M. R., 17 Oct 2023, In: Journal of thrombosis and haemostasis : JTH. 21, 11, p. 3236-3251 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile106 Downloads (Pure)
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MRC IAA (Internal) Further development and characterisation of a bispecific nanobody to GPVI and human serum albumin as a novel anti-thrombotic therapy
Poulter, N. (Principal Investigator), Thomas, M. R. (Co-Investigator), Slater, A. (Co-Investigator) & Watson, S. (Co-Investigator)
1/03/25 → 31/03/26
Project: Research Councils
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Studying the full-length structure of the GPVI receptor complex in the membrane: Identifying novel sites of selective inhibition and antiplatelet activity
Slater, A. (Principal Investigator) & Watson, S. (Co-Investigator)
1/10/24 → 30/09/29
Project: Research
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MRC IAA Development of a bivalent nanobody to GPVI and human albumin as a novel anti-thrombotic therapy
Watson, S. (Co-Investigator), Thomas, M. R. (Co-Investigator), Slater, A. (Co-Investigator) & Poulter, N. (Principal Investigator)
1/02/24 → 31/12/25
Project: Research Councils
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Development of a novel strategy to reduce inflammation-driven clotting in sepsis
Slater, A. (Co-Investigator) & Rayes, J. (Principal Investigator)
The Stoneygate Trust, Sepsis Research (FEAT), ROSETREES TRUST
1/06/25 → 31/05/26
Project: Research
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BHF Accelerator: Characterizing the interaction of glycoprotein VI with GPIb-V-IX
Slater, A. (Principal Investigator)
1/06/23 → 1/06/24
Project: Research
Datasets
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Research data supporting "Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3Kbeta"
Kardeby, C. (Creator), Evans, A. (Creator), Campos, J. (Creator), Smith, C. (Creator), Slater, A. (Creator), Al-Wahaibi, A. M. (Creator), Slater, E. (Creator), Severin, S. (Creator), Brill, A. (Creator), Pejler, G. (Creator), Sun, Y. (Creator) & Watson, S. (Creator), University of Birmingham, 7 Nov 2022
DOI: 10.25500/edata.bham.00000758
Dataset