Alex Sinclair

Research output

Research output per year 2006 2018 2019 2020 2021 2022 2023 2024

• 106 Article
• 16 Review article
• 4 Paper
• 4 Comment/debate
• 11 More
  • 4 Letter
  • 3 Abstract
  • 1 Book
  • 1 Chapter
  • 1 Editorial
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2024

  A systematic review of optical coherence tomography findings in adults with mild traumatic brain injury

  Lyons, H., Sassani, M., Hyder, Y. F., Mitchell, J., Thaller, M., Mollan, S., Sinclair, A., Blanch, R., Waitt, A. & Karavitaki, N., 18 Jan 2024, (E-pub ahead of print) In: Eye. 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Traumatic Brain Injury 100%
  • Tomography 76%
  • Systematic Review 74%
  • Brain Concussion 68%
  • Optical Coherence Tomography 54%
  38 Downloads (Pure)

• Does a Healthy Weight Body Mass Index at Onset of Idiopathic Intracranial Hypertension Change the Outcomes? A United Kingdom Prospective Cohort Study

  Thaller, M., Homer, V., Abbott, S., Hazlehurst, J., Mollan, S. P. & Sinclair, A. J., 22 Apr 2024, In: Neuro-Ophthalmology. 12 p., 2341775.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Hypertension 68%
  • Body Mass Index 52%
  • Cohort Studies 50%
  • Headache 48%
  17 Downloads (Pure)

• Effect of glucagon like peptide-1 receptor agonist exenatide, used as an intracranial pressure lowering agent, on cognition in Idiopathic Intracranial Hypertension

  Grech, O., Mitchell, J., Lyons, H., Yiangou, A., Thaller, M., Tsermoulas, G., Brock, K., Mollan, S. & Sinclair, A., 11 Jan 2024, (E-pub ahead of print) In: Eye. 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Exenatide 99%
  • Glucagon-Like Peptide-1 Receptor 94%
  • Hypertension 91%
  • Intracranial Pressure 80%
  11 Downloads (Pure)

• Evaluating the Phenotypic Patterns of Post-Traumatic Headache: A Systematic Review of Military Personnel

  UK mTBI Predict Consortium, Lyons, H. S., Sassani, M., Thaller, M., Yiangou, A., Grech, O., Mollan, S. P., Wilson, D. R., Lucas, S. J. E., Mitchell, J. L., Hill, L. J. & Sinclair, A. J., 19 Jul 2024, (E-pub ahead of print) In: Military medicine. 9 p., usae353.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File
  67 Downloads (Pure)

• Guidelines of the International Headache Society for controlled trials of pharmacological preventive treatment for persistent post-traumatic headache attributed to mild traumatic brain injury

  Ashina, H., Diener, H-C., Tassorelli, C., Scher, A. I., Lipton, R. B., Pozo-Rosich, P., Sinclair, A. J., Chong, C. D., Finkel, A. G., Ashina, M., Schwedt, T. J., Dodick, D. W. & Terwindt, G. M., 22 Mar 2024, In: Cephalalgia. 44, 3, p. 1-18 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Post-Traumatic Headache 100%
  • Brain Concussion 81%
  • Headache 54%
  • Pharmacology 42%
  • Guidelines 41%
  23 Downloads (Pure)

• Inhibition of the glucocorticoid‐activating enzyme 11β‐hydroxysteroid dehydrogenase type 1 drives concurrent 11‐oxygenated androgen excess

  Schiffer, L., Oestlund, I., Snoep, J. L., Gilligan, L. C., Taylor, A. E., Sinclair, A. J., Singhal, R., Freeman, A., Ajjan, R., Tiganescu, A., Arlt, W. & Storbeck, KH., 15 Apr 2024, In: FASEB Journal. 38, 7, 18 p., e23574.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Androgen 100%
  • Glucocorticoid 76%
  • Oxidoreductases 72%
  • Androgens 72%
  • Enzymes 43%
  37 Downloads (Pure)
• 2023

  A neuro-ophthalmologist’s guide to advances in intracranial pressure measurements

  Mollan, S., Momin, S. N. A., Khatkar, P. S., Grech, O., Sinclair, A. & Tsermoulas, G., 27 Sept 2023, In: Eye and Brain. 15, p. 113-124 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ophthalmologists 100%
  • Intracranial Pressure 98%
  • Neurosurgeons 34%
  • Neurologists 33%
  • Cerebrospinal Fluid 25%
  42 Downloads (Pure)

• Asymptomatic idiopathic intracranial hypertension: Prevalence and prognosis

  Thaller, M., Homer, V., Mollan, S. & Sinclair, A., 27 May 2023, (E-pub ahead of print) In: Clinical and Experimental Ophthalmology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Headache 41%
  • Papilledema 30%
  • Visual Fields 12%
  • Optical Coherence Tomography 12%
  83 Downloads (Pure)

• Comment on: ‘The expanding spectrum of idiopathic intracranial hypertension’

  Bilton, E. J., Sinclair, A. & Mollan, S., Oct 2023, In: Eye. 37, 1 p., 3049.

  Research output: Contribution to journal › Comment/debate › peer-review

• Comorbid polycystic ovarian syndrome in idiopathic intracranial hypertension

  Thaller, M., Adderley, N., Subramanian, A., Mollan, S. & Sinclair, A., 10 Jan 2023, In: Neuro-Ophthalmology. 47, 1, p. 49-52 4 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Polycystic Ovary Syndrome 81%
  • Fertility 22%
  • Weights and Measures 15%
  • Phenotype 14%
  31 Downloads (Pure)

• Considerations from venous stenosis to metabolic underpinnings in Idiopathic Intracranial Hypertension

  Thaller, M., Sinclair, A., Tsermoulas, G. & Mollan, S., 24 Jun 2023, In: Cephalalgia. 43, 6, p. 1-3 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File
  55 Downloads (Pure)

• Current and emerging diagnostic and management approaches for idiopathic intracranial hypertension

  Piccus, R., Thaller, M., Sinclair, A. & Mollan, S., 28 Apr 2023, (E-pub ahead of print) In: Expert Review of Neurotherapeutics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Papilledema 45%
  • Intracranial Pressure 40%
  • Metabolic Diseases 38%
  • Headache 31%
  35 Downloads (Pure)

• Defining the Phenotype and Prognosis of People With Idiopathic Intracranial Hypertension After Cerebrospinal Fluid Diversion Surgery

  Hyder, Y. F., Homer, V., Thaller, M., Byrne, M., Tsermoulas, G., Piccus, R., Mollan, S. P. & Sinclair, A. J., Jun 2023, In: American Journal of Ophthalmology. 250, p. 70-81 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Papilledema 76%
  • Cerebrospinal Fluid 63%
  • Phenotype 44%
  • Headache 41%
  67 Downloads (Pure)

• Depression and anxiety in women with idiopathic intracranial hypertension compared to migraine: a matched controlled cohort study

  Mollan, S., Subramanian, A., Perrins, M., Nirantharakumar, K., Adderley, N. & Sinclair, A., 15 Feb 2023, In: Headache. 63, p. 290-298 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Migraine Disorders 73%
  • Anxiety 52%
  • Cohort Studies 50%
  • Depression 48%
  152 Downloads (Pure)

• Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss

  Alimajstorovic, Z., Mitchell, J., Yiangou, A., Hancox, T., Southam, A., Grech, O., Ottridge, R., Winder, C., Tahrani, A., Tan, T. M., Mollan, S., Dunn, W. & Sinclair, A., 18 Oct 2023, (E-pub ahead of print) In: Brain Communications. 5, 5, 16 p., fcad272.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Intracranial Pressure 100%
  • Metabolic Networks and Pathways 91%
  • Weight Loss 74%
  • Glucagon-Like Peptide 1 64%
  • Pseudotumor Cerebri 62%
  109 Downloads (Pure)

• Disease Course and Long-term Outcomes in Pregnant Women With Idiopathic Intracranial Hypertension: The IIH Prospective Maternal Health Study

  Thaller, M., Homer, V., Mollan, S. P. & Sinclair, A. J., 11 Apr 2023, In: Neurology. 100, 15, p. E1598-E1610 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Pseudotumor Cerebri 100%
  • Maternal Health 83%
  • Pregnant Women 59%
  • Pregnancy 18%
  • Headache 9%

• Experimental drugs for the treatment of idiopathic intracranial hypertension (IIH): shedding light on phase I and II trials

  Khatkar, P., Hubbard, J. C., Hill, L., Sinclair, A. J. & Mollan, S. P., 25 Nov 2023, (E-pub ahead of print) In: Expert opinion on investigational drugs.

  Research output: Contribution to journal › Review article › peer-review

  • Pseudotumor Cerebri 100%
  • 2-(1-(5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl)-3-piperidyl)acetic acid 35%
  • Intracranial Pressure 32%
  • Pharmaceutical Preparations 30%
  • 11-beta-Hydroxysteroid Dehydrogenases 21%

• Guidelines of the International Headache Society for controlled clinical trials in idiopathic intracranial hypertension

  Mollan, S., Fraser, C. L., Digre, K. B., Diener, H-C., Lipton, R., Juhler, M., Miller, N. R., Pozo-Rosich, P., Togha, M., Brock, K., Dinkin, M., Chan, C. K. M., Tassorelli, C., Sinclair, A., Terwindt, G. M. & Jensen, R. H., 3 Sept 2023, (E-pub ahead of print) In: Cephalalgia. 43, 8, p. 1-25 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Controlled Clinical Trials 79%
  • Headache 62%
  • Guidelines 47%
  • Clinical Trials 31%
  70 Downloads (Pure)

• Identification of a human blood biomarker of pharmacological 11β‐hydroxysteroid dehydrogenase 1 inhibition

  Gómez, C., Alimajstorovic, Z., Othonos, N., Winter, D. V., White, S., Lavery, G. G., Tomlinson, J. W., Sinclair, A. J. & Odermatt, A., 23 Sept 2023, (E-pub ahead of print) In: British Journal of Pharmacology. 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pharmacological Biomarkers 100%
  • Forensic Anthropology 74%
  • glycoursodeoxycholic acid 72%
  • Oxidoreductases 52%
  • Psychological Inhibition 47%
  38 Downloads (Pure)

• Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms

  Yiangou, A., Mollan, S. & Sinclair, A., 13 Nov 2023, (E-pub ahead of print) In: Nature Reviews Neurology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Pressure 32%
  • Metabolic Diseases 30%
  • Obesity 30%
  • Headache 25%
  48 Downloads (Pure)

• Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess

  Schiffer, L., Oestlund, I., Snoep, J., Gilligan, L. C., Taylor, A. E., Sinclair, A. J., Singhal, R., Freeman, A., Ajjan, R., Tiganescu, A., Arlt, W. & Storbeck, K-H., 9 Jun 2023, bioRxiv.

  Research output: Working paper/Preprint › Preprint

  • Aldo-Keto Reductases 100%
  • 11-beta-Hydroxysteroid Dehydrogenases 93%
  • 11-ketotestosterone 83%
  • Androgens 58%
  • Glucocorticoids 58%

• Interpretation of telemetric intracranial pressure recordings in people with Idiopathic Intracranial Hypertension after shunt implantation

  Afshari, F. T., Samara, M., Thant, K. Z., Byrne, M., Sinclair, A., Mollan, S. & Tsermoulas, G., 18 Apr 2023, (E-pub ahead of print) In: Acta Neurochirurgica. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Pressure 80%
  • Ventriculoperitoneal Shunt 21%
  • Supine Position 18%
  • Sitting Position 17%
  22 Downloads (Pure)

• Longitudinal prospective cohort study evaluating prognosis in idiopathic intracranial hypertension patients with and without comorbid polycystic ovarian syndrome

  Thaller, M., Homer, V., Sassani, M., Mollan, S. P. & Sinclair, A. J., 24 May 2023, (E-pub ahead of print) In: Eye (London, England).

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Hypertension 91%
  • Polycystic Ovary Syndrome 81%
  • Cohort 80%
  • Syndrome 64%
  44 Downloads (Pure)

• Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production

  Wardman, J. H., Jensen, M. N., Andreassen, S. N., Styrishave, B., Wilhjelm, J. E., Sinclair, A. J. & MacAulay, N., 16 Jun 2023, In: Fluids and barriers of the CNS. 20, 1, 17 p., 44.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Pressure 80%
  • High Fat Diet 73%
  • Testosterone 64%
  • Cerebrospinal Fluid 63%
  33 Downloads (Pure)

• The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

  Mitchell, J. L., Lyons, H. S., Walker, J. K., Yiangou, A., Grech, O., Alimajstorovic, Z., Greig, N. H., Li, Y., Tsermoulas, G., Brock, K., Mollan, S. P. & Sinclair, A. J., 1 May 2023, In: Brain. 146, 5, p. 1821-1830 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Exenatide 99%
  • Intracranial Pressure 80%
  • Randomized Controlled Trials 49%
  • Glucagon-Like Peptide-1 Receptor 28%
  73 Downloads (Pure)

• The Impact of Valsalva Manoeuvres and Exercise on Intracranial Pressure and Cerebrovascular Dynamics in Idiopathic Intracranial Hypertension

  Yiangou, A., Weaver, S. R. C., Thaller, M., Mitchell, J. L., Lyons, H. S., Tsermoulas, G., Mollan, S. P., Lucas, S. J. E. & Sinclair, A. J., 22 Nov 2023, (E-pub ahead of print) In: Neuro-Ophthalmology. 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Valsalva Maneuver 96%
  • Intracranial Pressure 80%
  • Hemodynamics 19%
  • Intracranial Hypertension 15%
  26 Downloads (Pure)

• Visual field Pointwise Analysis of the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT)

  Mollan, S., Bodoza, S., Ní Mhéalóid, Á., Mitchell, J., Miller, N. R., Montesano, G., Crabb, D. P., Wall, M., Brock, K. & Sinclair, A., 1 May 2023, In: Translational Vision Science & Technology. 12, 5, 11 p., 1.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Visual Fields 73%
  • Weights and Measures 46%
  • Optic Disk 16%
  • Randomized Controlled Trials 9%
  40 Downloads (Pure)
• 2022

  Alterations in metabolic flux in migraine and the translational relevance

  Grech, O., Sassani, M., Terwindt, G., Lavery, G., Mollan, S. & Sinclair, A., 30 Sept 2022, (E-pub ahead of print) In: The Journal of Headache and Pain. 23, 1, 12 p., 127.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Migraine Disorders 100%
  • Nociception 33%
  • Calcitonin Gene-Related Peptide 33%
  • Cortical Spreading Depression 21%
  • Biomarkers 18%
  59 Downloads (Pure)

• Association of amount of weight lost after bariatric surgery with intracranial pressure in women with idiopathic intracranial hypertension

  Mollan, S. P., Mitchell, J. L., Yiangou, A., Ottridge, R. S., Alimajstorovic, Z., Cartwright, D. M., Hickman, S. J., Markey, K. A., Singhal, R., Tahrani, A. A., Frew, E., Brock, K. & Sinclair, A. J., 13 Sept 2022, In: Neurology. 99, 11, p. e1090-e1099 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Bariatric Surgery 81%
  • Intracranial Pressure 80%
  • Weight Loss 60%
  • Weights and Measures 46%
  135 Downloads (Pure)

• Dysregulation of amino acid, lipid and acylpyruvate metabolism in idiopathic intracranial hypertension: a non-targeted case control and longitudinal metabolomic study

  Alimajstorovic, Z., Mollan, S., Grech, O., Mitchell, J., Yiangou, A., Thaller, M., Lyons, H., Sassani, M., Seneviratne, S., Hancox, T., Jankevics, A., Najdekr, L., Dunn, W. & Sinclair, A., 19 Dec 2022, (E-pub ahead of print) In: Journal of Proteome Research. 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Intracranial 100%
  • Pseudotumor Cerebri 85%
  • Metabolomics 68%
  • Lipid Metabolism 60%
  • Longitudinal Studies 52%
  103 Downloads (Pure)

• European Headache Federation (EHF) consensus on the definition of effective treatment of a migraine attack and of triptan failure

  Sacco, S., Lampl, C., Amin, F. M., Braschinsky, M., Deligianni, C., Uludüz, D., Versijpt, J., Ducros, A., Gil-Gouveia, R., Katsarava, Z., Martelletti, P., Ornello, R., Raffaelli, B., Boucherie, D. M., Pozo-Rosich, P., Sanchez-Del-Rio, M., Sinclair, A., Maassen van den brink, A. & Reuter, U., 12 Oct 2022, In: The Journal of Headache and Pain. 23, 1, p. 133 10 p., 133.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Tryptamines 100%
  • Migraine Disorders 71%
  • Headache 60%
  • Therapeutics 11%
  • Contraindications 4%
  77 Downloads (Pure)

• Evaluation of diurnal and postural intracranial pressure employing telemetric monitoring in idiopathic intracranial hypertension

  Mitchell, J., Buckham, R., Lyons, H., Walker, J., Yiangou, A., Sassani, M., Thaller, M., Grech, O., Alimajstorovic, Z., Julher, M., Tsermoulas, G., Brock, K., Mollan, S. & Sinclair, A., 1 Nov 2022, In: Fluids and barriers of the CNS. 19, 1, 11 p., 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Supine Position 81%
  • Intracranial Pressure 80%
  • Sitting Position 15%
  • Posture 14%
  73 Downloads (Pure)

• Headache, opiate use, and prescribing trends in women with idiopathic intracranial hypertension: a population-based matched cohort study

  Adderley, N., Subramanian, A., Perrins, M., Nirantharakumar, K., Mollan, S. & Sinclair, A., 19 Aug 2022, (E-pub ahead of print) In: Neurology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Opiate Alkaloids 79%
  • Headache 62%
  • Cohort Studies 50%
  • Migraine Disorders 41%
  88 Downloads (Pure)

• Idiopathic intracranial hypertension: Evaluation of births and fertility through the Hospital Episode Statistics dataset

  Thaller, M., Mytton, J., Wakerley, B., Mollan, S. & Sinclair, A., 27 May 2022, (E-pub ahead of print) In: BJOG: An International Journal of Obstetrics & Gynaecology. 129, 12, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Fertility 68%
  • Datasets 57%
  • Statistics 56%
  • Parturition 50%
  128 Downloads (Pure)

• Increased systemic and adipose 11β-HSD1 activity in idiopathic intracranial hypertension

  Westgate, C. S. J., Markey, K., Mitchell, J. L., Yiangou, A., Singhal, R., Stewart, P., Tomlinson, J. W., Lavery, G. G., Mollan, S. P. & Sinclair, A. J., 1 Aug 2022, In: European Journal of Endocrinology. 187, 2, p. 323–333 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Glucocorticoids 30%
  • Bariatric Surgery 22%
  • Intracranial Pressure 21%
  • Weight Loss 16%
  49 Downloads (Pure)

• Letter: Cerebrospinal fluid shunting for idiopathic intracranial hypertension: a systematic review, meta-analysis, and implications for a modern management protocol

  Mollan, S., Sinclair, A. & Tsermoulas, G., 29 Dec 2022, (E-pub ahead of print) In: Neurosurgery. 2 p., 10.1227/neu.0000000000002316.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  25 Downloads (Pure)

• Managing idiopathic intracranial hypertension in pregnancy: practical advice

  Thaller, M., Wakerley, B., Abbott, S., Tahrani, A., Mollan, S. & Sinclair, A., Aug 2022, In: Practical Neurology. 22, 4, p. 295-300 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Pregnancy 44%
  • Acetazolamide 26%
  • Gestational Weight Gain 26%
  • Topiramate 13%
  51 Downloads (Pure)

• Multiple lumbar punctures aiming to relieve headache results in iatrogenic spinal haematoma: a case report

  Lyons, H. S., Ramalingam, S., Mitchell, J. L., Yiangou, A., Thaller, M., Sinclair, A. J. & Mollan, S. P., 14 Dec 2022, In: Journal of medical case reports. 16, 1, 7 p., 464 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Spinal Puncture 100%
  • Hematoma 78%
  • Headache 71%
  • Pseudotumor Cerebri 30%
  • Paresthesia 19%
  99 Downloads (Pure)

• Nuclear magnetic resonance spectroscopy metabolomics in Idiopathic Intracranial Hypertension to identify markers of disease and headache

  Grech, O., Seneviratne, S., Alimajstorovic, Z., Yiangou, A., Mitchell, J., Smith, T., Mollan, S., Lavery, G., Ludwig, C. & Sinclair, A., 8 Sept 2022, (E-pub ahead of print) In: Neurology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Metabolomics 80%
  • Headache 62%
  • Magnetic Resonance Spectroscopy 61%
  • Urine 22%
  53 Downloads (Pure)

• The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes

  Thaller, M., Homer, V., Hyder, Y., Yiangou, A., Liczkowski, A., Fong, A., Virdee, J., Piccus, R., Roque, M., Mollan, S. & Sinclair, A., 15 Oct 2022, (E-pub ahead of print) In: Journal of Neurology. 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Headache 62%
  • Cohort Studies 50%
  • Prospective Studies 46%
  • Optical Coherence Tomography 43%
  122 Downloads (Pure)
• 2021

  11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension

  Hardy, R., Botfield, H., Markey, K., Mitchell, J., Alimajstorovic, Z., Westgate, C., Sagmeister, M., Fairclough, R., Ottridge, R., Yiangou, A., Storbeck, K-H., Taylor, A., Gilligan, L., Arlt, W., Stewart, P., Tomlinson, J., Mollan, S., Lavery, G. & Sinclair, A., 1 Jan 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. 174-187 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • 2-(1-(5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl)-3-piperidyl)acetic acid 100%
  • Intracranial 65%
  • Pseudotumor Cerebri 55%
  • 11-beta-Hydroxysteroid Dehydrogenases 39%
  • Marker 35%
  4 Citations (Scopus)

  215 Downloads (Pure)

• Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance

  Burden and Attitude to Resistant and Refractory (BARR) Study Group, Sacco, S., Lampl, C., Maassen Van Den Brink, A., Caponnetto, V., Braschinsky, M., Ducros, A., Little, P., Pozo-Rosich, P., Reuter, U., Ruiz De La Torre, E., Sanchez Del Rio, M., Sinclair, A., Martelletti, P. & Katsarava, Z., 18 May 2021, In: The Journal of Headache and Pain. 22, 1, 39.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Migraine Disorders 100%
  • Headache 85%
  • Consensus 14%
  • Physicians 14%
  • Therapeutics 7%
  254 Downloads (Pure)

• Cerebrospinal fluid shunting protocol for Idiopathic Intracranial Hypertension improves revision rate

  Galloway, L., Karia, K., White, A., Byrne, M., Sinclair, A., Mollan, S. & Tsermoulas, G., 21 May 2021, (Accepted/In press) In: Journal of Neurosurgery.

  Research output: Contribution to journal › Article › peer-review

• Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure

  Grech, O., Clouter, A., Mitchell, J., Alimajstorovic, Z., Ottridge, R., Yiangou, A., Roque, M., Tahrani, A., Nicholls, M., Taylor, A., Shaheen, F., Arlt, W., Lavery, G., Shapiro, K., Mollan, S. & Sinclair, A., 2 Sept 2021, In: Brain Communications. 3, 3, 14 p., fcab202.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Pressure 80%
  • Cognition 33%
  • Obstructive Sleep Apnea 32%
  • Hydrocortisone 27%
  299 Downloads (Pure)

• Cost-effectiveness of bariatric surgery versus community weight management to treat obesity-related idiopathic intracranial hypertension: evidence from a single payer health care system

  Elliot, L., Frew, E., Mollan, S., Mitchell, J., Yiangou, A., Alimajstorovic, Z., Ottridge, R., Wakerley, B., Thaller, M., Grech, O., Singhal, R., Tahrani, A., Harrison, M., Sinclair, A. & Aguiar, M., 1 Jul 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. P1310-1316

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Intracranial Hypertension 87%
  • Bariatric Surgery 81%
  • Cost-Benefit Analysis 63%
  • Obesity 51%
  198 Downloads (Pure)

• Current perspectives on idiopathic intracranial hypertension without papilloedema

  Mollan, S., Chong, Y. J., Grech, O., Sinclair, A. & Wakerley, B., 24 May 2021, In: Life. 11, 6, 472.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Papilledema 91%
  • Idiopathic intracranial hypertension with papilledema 37%
  • Intracranial Pressure 30%
  • Headache 23%
  185 Downloads (Pure)

• Diagnosis and management of migraine in ten steps: consensus statement

  Eigenbrodt, A., Ashina, H., Khan, S., Diener, H-C., Mitsikostas, D., Sinclair, A., Pozo-Rosich, P., Martelletti, P., Ducros, A., Lanteri-Minet, M., Braschinsky, M., Sanchez Del Rio, M., Daniel, O., Ozge, A., Mammadbayli, A., Arons, M., Skorobogatykh, K., Romanenko, V., Terwindt, G., Paemeleire, K., & 7 othersSacco, S., Reuter, U., Lampl, C., Schytz, H. W., Katsarava, Z., Steiner, T. & Ashina, M., 18 Jun 2021, (E-pub ahead of print) In: Nature Reviews Neurology.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Migraine Disorders 100%
  • Consensus 94%
  • Primary Headache Disorders 28%
  • Treatment Adherence and Compliance 22%
  • Neurology 21%
  179 Downloads (Pure)

• Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension: A Randomized Clinical Trial

  Mollan, S., Mitchell, J., Ottridge, R., Aguiar, M., Alimajstorovic, Z., Cartwright, D., Grech, O., Lavery, G., Westgate, C., Vijay, V., Scotton, W., Wakerley, B., Matthews, T., Ansons, A., Hickman, S., Benzimra, J., Rick, C., Singhal, R., Tahrani, A., Brock, K., & 2 othersFrew, E. & Sinclair, A., 1 Jun 2021, In: JAMA Neurology. 78, 6, p. 678-686

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudotumor Cerebri 100%
  • Bariatric Surgery 81%
  • Cerebrospinal Fluid 63%
  • Randomized Controlled Trials 49%
  • Weights and Measures 46%
  4 Citations (Scopus)

  175 Downloads (Pure)

• Erenumab for headaches in idiopathic intracranial hypertension: a prospective open-label evaluation

  Yiangou, A., Mitchell, J., Fisher, C., Edwards, J., Vijay, V., Alimajstorovic, Z., Grech, O., Lavery, G., Mollan, S. & Sinclair, A., 27 Jan 2021, In: Headache. 61, 1, p. 157-169

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • erenumab 100%
  • Pseudotumor Cerebri 71%
  • Headache 45%
  • Papilledema 14%
  • Prescription Drug Overuse 5%
  313 Downloads (Pure)

• Green flags and headache: a concept study using the Delphi method

  Pohl, H., Phu Do, T., Garcia-Azorin, D., Hansen, J. M., Saxhaug Kristoffersen, E., Nelson, S. E., Obermann, M., Sandor, P., Schankin, C., Schytz, H. W., Sinclair, A., Schoonman, G. G. & Gantenbein, A. R., 6 Jan 2021, (E-pub ahead of print) In: Headache. 2021, 00, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Delphi Technique 100%
  • Headache 63%
  • Consensus 20%
  • Primary Headache Disorders 15%
  • Resource Allocation 12%
  1 Citation (Scopus)