Alan McNally

Research output

Research output per year 2004 2017 2018 2019 2021 2022 2023 2024

• 104 Article
• 9 Review article
• 3 Comment/debate
• 3 Letter

Research output per year

Research output per year

Search results

• 2024

  Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone

  Ba, X., Guo, Y., Moran, R. A., Doughty, E. L., Liu, B., Yao, L., Li, J., He, N., Shen, S., Li, Y., van Schaik, W., Mcnally, A., Holmes, M. A. & Zhuo, C., 12 Jan 2024, In: Nature Communications. 15, 1, 15 p., 494.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Escherichia 100%
  • Carbapenems 96%
  • Clone Cells 66%
  • plasmids 58%
  • Escherichia coli 58%
  3 Downloads (Pure)

• Modulation of multidrug-resistant clone success in Escherichia coli populations: a longitudinal, multi-country, genomic and antibiotic usage cohort study

  Pöntinen, A. K., Gladstone, R. A., Pesonen, H., Pesonen, M., Cléon, F., Parcell, B. J., Kallonen, T., Simonsen, G. S., Croucher, N. J., McNally, A., Parkhill, J., Johnsen, P. J., Samuelsen, Ø. & Corander, J., 4 Jan 2024, (E-pub ahead of print) In: The Lancet. Microbe.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lactams 100%
  • Clone Cells 97%
  • Escherichia coli 86%
  • Cohort Studies 83%
  • Anti-Bacterial Agents 80%
  12 Downloads (Pure)

• Multidrug resistance plasmids commonly reprogram the expression of metabolic genes in Escherichia coli

  Hall, R. J., Snaith, A. E., Thomas, M. J. N., Brockhurst, M. A. & McNally, A., 1 Mar 2024, In: mSystems. 9, 3, e0119323.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiple Drug Resistance 100%
  • Plasmids 77%
  • Escherichia coli 67%
  • Gene Expression 57%
  • Colistin 15%

• Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics

  Hall, R. J., Snaith, A. E., Element, S. J., Moran, R. A., Smith, H., Cummins, E. A., Bottery, M. J., Chowdhury, K. F., Sareen, D., Ahmad, I., Blair, J. M. A., Carter, L. J. & McNally, A., 15 Apr 2024, In: npj Antimicrobials and Resistance. 2, 1, 8 p., 11 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • antibiotics 100%
  • drug 82%
  • exposure 57%
  • toxicity 29%
  • titanium dioxide 24%

• Safety and efficacy of phage application in bacterial decolonisation: a systematic review

  Fang, Q., Ying, X., He, Y., Feng, Y., Zhang, L., Luo, H., Yin, G., McNally, A. & Zong, Z., 4 Mar 2024, (E-pub ahead of print) In: The Lancet. Microbe.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Bacteriophages 100%
  • Systematic Reviews 74%
  • Safety 58%
  • Bacteria 22%
  • Library Science 22%
  33 Downloads (Pure)

• Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol

  Quarton, S., McGee, K., Cumley, N., Behruznia, M., Jeff, C., Belchamber, K., Cox, M., Thickett, D., Scott, A., Parekh, D., McNally, A. & Sapey, E., 29 Mar 2024, In: PLoS ONE. 19, 3, 12 p., e0298425.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Observational Studies 100%
  • therapeutics 99%
  • protocols 91%
  • Antimicrobial Agent 89%
  • genomics 81%
• 2023

  E. coli ST11 (O157:H7) does not encode a functional AcrF efflux pump

  Pugh, H. L., Connor, C., Siasat, P., McNally, A. & Blair, J. M. A., 19 Apr 2023, In: Microbiology. 169, 4, 001324.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Escherichia coli O157 100%
  • Escherichia coli 55%
  • Terminator Codon 10%
  • Gram-Negative Bacteria 8%
  • Amino Acids 6%
  18 Downloads (Pure)

• Endemicity and diversification of carbapenem-resistant Acinetobacter baumannii in an intensive care unit

  Doughty, E. L., Liu, H., Moran, R. A., Hua, X., Ba, X., Guo, F., Chen, X., Zhang, L., Holmes, M., van Schaik, W., McNally, A. & Yu, Y., 8 May 2023, (E-pub ahead of print) In: The Lancet regional health. Western Pacific. 37, 10 p., 100780.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Acinetobacter baumannii 100%
  • Carbapenems 95%
  • Intensive Care Units 68%
  • China 18%
  • Disease Outbreaks 13%
  48 Downloads (Pure)

• Evolutionary and functional history of the Escherichia coli K1 capsule

  Arredondo-Alonso, S., Blundell-Hunter, G., Fu, Z., Gladstone, R. A., Fillol-Salom, A., Loraine, J., Cloutman-Green, E., Johnsen, P. J., Samuelsen, Ø., Pöntinen, A. K., Cléon, F., Chavez-Bueno, S., De la Cruz, M. A., Ares, M. A., Vongsouvath, M., Chmielarczyk, A., Horner, C., Klein, N., McNally, A., Reis, J. N., & 5 othersPenadés, J. R., Thomson, N. R., Corander, J., Taylor, P. W. & McCarthy, A. J., 15 Jun 2023, In: Nature Communications. 14, 1, 3294 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Virulence Factor 100%
  • Escherichia 86%
  • capsules 81%
  • infectious diseases 72%
  • Capsules 64%
  20 Downloads (Pure)

• Evolutionary responses to acquiring a multidrug resistance plasmid are dominated by metabolic functions across diverse Escherichia coli lineages

  Carrilero, L., Dunn, S. J., Moran, R. A., McNally, A. & Brockhurst, M. A., 1 Feb 2023, (E-pub ahead of print) In: mSystems. 15 p., e0071322.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiple Drug Resistance 100%
  • Plasmids 77%
  • Escherichia coli 67%
  • Bacterial Genomes 29%
  • Anaerobiosis 19%
  26 Downloads (Pure)

• Extended-Spectrum β-Lactamase Genes Traverse the Escherichia coli Populations of Intensive Care Unit Patients, Staff, and Environment

  Moran, R. A., Baomo, L., Doughty, E. L., Guo, Y., Ba, X., van Schaik, W., Zhuo, C. & McNally, A., 14 Mar 2023, In: Microbiology spectrum. 11, 2, 14 p., e0507422.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • plasmid 100%
  • Intensive Care Units 68%
  • Plasmids 66%
  • plasmids 62%
  • gene 62%
  41 Downloads (Pure)

• Hijacking a small plasmid to confer high-level resistance to aztreonam-avibactam and ceftazidime-avibactam

  Ma, K., Feng, Y., McNally, A. & Zong, Z., 27 Sept 2023, (E-pub ahead of print) In: International Journal of Antimicrobial Agents. 106985.

  Research output: Contribution to journal › Article › peer-review

  • ceftazidime drug combination avibactam 100%
  • Aztreonam 82%
  • Plasmids 48%
  • avibactam 44%
  • Carbapenems 19%

• Metallo-β-lactamase-mediated antimicrobial resistance and progress in inhibitor discovery

  Yang, Y., Yan, Y-H., Schofield, C. J., McNally, A., Zong, Z. & Li, G-B., 27 Feb 2023, (E-pub ahead of print) In: Trends in Microbiology.

  Research output: Contribution to journal › Review article › peer-review

  • Lactams 100%
  • Anti-Bacterial Agents 34%
  • Hydrolysis 32%
  • Monobactams 27%
  • Serine 17%

• Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

  Connor, C. H., Zucoloto, A. Z., Munnoch, J. T., Yu, I., Corander, J., Hoskisson, P. A., Mcdonald, B. & Mcnally, A., 17 Oct 2023, In: PLoS Biology. 21, 10, e3002329.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carbohydrate Metabolism 100%
  • carbohydrate metabolism 92%
  • Genetic Variation 84%
  • multiple drug resistance 82%
  • intestines 72%
  14 Downloads (Pure)

• Parallel loss of type VI secretion systems in two multi-drug-resistant Escherichia coli lineages

  Cummins, E. A., Moran, R. A., Snaith, A. E., Hall, R. J., Connor, C. H., Dunn, S. J. & McNally, A., 16 Nov 2023, In: Microbial Genomics. 9, 11, 001133.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VI Secretion Systems 100%
  • Escherichia coli 44%
  • Clone Cells 33%
  • Pharmaceutical Preparations 26%
  • Genes 16%
  7 Downloads (Pure)

• Phytoremediation as a Tool to Remove Drivers of Antimicrobial Resistance in the Aquatic Environment

  Chowdhury, K. F., Hall, R. J., McNally, A. & Carter, L. J., Dec 2023, In: Reviews of Environmental Contamination and Toxicology. 261, 1, 16.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • phytoremediation 100%
  • aquatic environment 85%
  • pollutant 41%
  • macrophyte 36%
  • chemical 34%
  37 Downloads (Pure)

• Prevalence and clonal diversity of carbapenem-resistant Klebsiella pneumoniae causing neonatal infections: A systematic review of 128 articles across 30 countries

  Hu, Y., Yang, Y., Feng, Y., Fang, Q., Wang, C., Zhao, F., McNally, A. & Zong, Z., 20 Jun 2023, In: PLoS Medicine. 20, 6, 30 p., e1004233.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carbapenems 100%
  • Klebsiella pneumoniae 91%
  • Systematic Reviews 63%
  • Infections 41%
  • Klebsiella Infections 38%
  36 Downloads (Pure)

• RND pumps across the genus Acinetobacter: AdeIJK is the universal efflux pump

  Darby, E. M., Bavro, V. N., Dunn, S., Mcnally, A. & Blair, J. M. A., 30 Mar 2023, In: Microbial Genomics. 9, 3, 000964.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Acinetobacter 100%
  • nodulation 88%
  • pumps 79%
  • transporters 73%
  • infection 22%
  9 Downloads (Pure)

• The Effect of β-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae

  Zhang, P., Hu, H., Shi, Q., Sun, L., Wu, X., Hua, X., McNally, A., Jiang, Y., Yu, Y. & Du, X., 16 Feb 2023, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy. e0127922.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • cefiderocol 100%
  • ceftazidime drug combination avibactam 85%
  • Lactams 73%
  • carbapenemase 69%
  • Klebsiella pneumoniae 54%
  24 Downloads (Pure)

• The highly diverse plasmid population found in Escherichia coli colonizing travellers to Laos and its role in antimicrobial resistance gene carriage

  Snaith, A. E., Dunn, S. J., Moran, R. A., Newton, P. N., Dance, D. A. B., Davong, V., Kuenzli, E., Kantele, A., Corander, J. & McNally, A., 12 May 2023, In: Microbial Genomics. 9, 5, 001000.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Laos 100%
  • Plasmids 54%
  • Escherichia coli 47%
  • Genes 27%
  • Population 26%
  20 Downloads (Pure)
• 2022

  Arm race among closely-related carbapenem-resistant Klebsiella pneumoniae clones

  Liu, Y., Zhu, S., Wei, L., Feng, Y., Cai, L., Dunn, S., McNally, A. & Zong, Z., 22 Aug 2022, In: ISME Communications. 2, 1, 76.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carbapenems 100%
  • Klebsiella pneumoniae 91%
  • Clone Cells 68%
  • Ethanolamine 23%
  • Virulence 10%
  30 Downloads (Pure)

• Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice

  Fang, Q., Feng, Y., McNally, A. & Zong, Z., Dec 2022, In: Communications Biology. 5, 1, 14 p., 48.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • carbapenems 100%
  • Carbapenems 86%
  • Klebsiella pneumoniae 84%
  • Bacteriophages 73%
  • phages 68%
  35 Downloads (Pure)

• Competitive transmission of carbapenem-resistant Klebsiella pneumoniae in a newly opened intensive care unit

  Hu, Y., Zhang, H., Wei, L., Feng, Y., Wen, H., Li, J., Zhang, Z., Yang, Y., Moran, R. A., McNally, A. & Zong, Z., Dec 2022, In: mSystems. 7, 6, 14 p., e0079922.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carbapenems 100%
  • Klebsiella pneumoniae 91%
  • Intensive Care Units 71%
  • Clone Cells 22%
  • Environmental Monitoring 16%
  24 Downloads (Pure)

• COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

  The COVID-19 Genomics U. K. (COG-UK) Consortium, Modat, M., Hammers, A., Spector, T. D., Steves, C. J., Sudre, C. H., Ourselin, S. & Duncan, E. L., Dec 2022, In: Scientific Reports. 12, 1, 17 p., 10904.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Hepatitis D 59%
  • Observational Studies 52%
  • Cohort Studies 46%
  • Infections 32%
  1 Citation (Scopus)

  24 Downloads (Pure)

• Covid-19 testing in the UK was not a "shambles" in 2020

  McNally, A., 12 Apr 2022, In: BMJ. 377, p. o916 o916.

  Research output: Contribution to journal › Letter › peer-review

• Distinct evolutionary trajectories in the Escherichia coli pangenome occur within sequence types

  Cummins, E. A., Hall, R. J., Connor, C., Mcinerney, J. O. & Mcnally, A., 23 Nov 2022, In: Microbial Genomics. 8, 11, 13 p., 000903.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Escherichia coli 100%
  • Genes 57%
  • Alleles 26%
  • Cell Membrane 25%
  • Genome 24%
  44 Downloads (Pure)

• Enterobacteriaceae and Bacteroidaceae provide resistance to travel-associated intestinal colonization by multi-drug resistant Escherichia coli

  Davies, M., Galazzo, G., van Hattem, J. M., Arcilla, M. S., Melles, D. C., de Jong, M. D., Schultsz, C., Wolffs, P., McNally, A., Schaik, W. V. & Penders, J., 7 Apr 2022, In: Gut Microbes. 14, 1, 2060676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bacteroidaceae 100%
  • Enterobacteriaceae 63%
  • beta-Lactamases 51%
  • Escherichia coli 40%
  • Pharmaceutical Preparations 23%
  62 Downloads (Pure)

• Fine-scale reconstruction of the evolution of FII-33 multidrug resistance plasmids enables high-resolution genomic surveillance

  Hu, Y., Moran, R. A., Blackwell, G. A., McNally, A. & Zong, Z., 22 Feb 2022, In: mSystems. 7, 1, 12 p., e0083121.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Surveillance 100%
  • High Resolution 94%
  • plasmid 93%
  • Cointegration 91%
  • Genomics 90%
  53 Downloads (Pure)

• Genomics and pathotypes of the many faces of Escherichia coli

  Geurtsen, J., de Been, M., Weerdenburg, E., Zomer, A., McNally, A. & Poolman, J., Nov 2022, In: FEMS Microbiology Reviews. 46, 6, 30 p., fuac031.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genomics 100%
  • Escherichia coli 69%
  • Extraintestinal Pathogenic Escherichia coli 53%
  • Symbiosis 22%
  • Genome 22%
  86 Downloads (Pure)

• GR13-type plasmids in Acinetobacter potentiate the accumulation and horizontal transfer of diverse accessory genes

  Moran, R. A., Liu, H., Doughty, E. L., Hua, X., Cummins, E. A., Liveikis, T., McNally, A., Zhou, Z., van Schaik, W. & Yu, Y., 22 Jun 2022, In: Microbial Genomics. 8, 6, 14 p., 000840.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Acinetobacter 100%
  • Plasmids 64%
  • Genes 32%
  • Recombinases 21%
  • Microbial Drug Resistance 16%
  62 Downloads (Pure)

• Klebsiella oxytoca complex: update on taxonomy, antimicrobial resistance, and virulence

  Yang, J., Long, H., Hu, Y., Feng, Y., McNally, A. & Zong, Z., 19 Jan 2022, In: Clinical Microbiology Reviews . 35, 1, e0000621.

  Research output: Contribution to journal › Review article › peer-review

  • Klebsiella oxytoca 100%
  • Klebsiella 79%
  • taxonomy 63%
  • Virulence 58%
  • Pseudomembranous Enterocolitis 38%

• Prokaryote pangenomes are dynamic entities

  Cummins, E. A., Hall, R. J., McInerney, J. O. & McNally, A., Apr 2022, In: Current Opinion in Microbiology. 66, p. 73-78 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Terminology 100%
  • Genes 79%
  79 Downloads (Pure)

• SARS-CoV-2 testing in the community: testing positive samples with the TaqMan SARS-CoV-2 mutation panel to find variants in real time

  COVID-19 Genomics UK (COG-UK) Consortium, 4 Apr 2022, In: Journal of Clinical Microbiology. 60, 4, e0240821.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Mutation 37%
  • Genome 18%
  • Genomics 13%
  • Health 6%
  30 Downloads (Pure)

• Strong pathogen competition in neonatal gut colonisation

  Mäklin, T., Thorpe, H. A., Pöntinen, A. K., Gladstone, R. A., Shao, Y., Pesonen, M., McNally, A., Johnsen, P. J., Samuelsen, Ø., Lawley, T. D., Honkela, A. & Corander, J., 1 Dec 2022, In: Nature Communications. 13, 1, 13 p., 7417.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • pathogens 100%
  • Ecosystem 85%
  • Klebsiella 61%
  • Strain 49%
  • Metagenomics 44%
  21 Downloads (Pure)

• Whole-genome sequencing enhances existing pathogen and antimicrobial-resistance surveillance schemes within a neonatal unit

  Price, V., Dunn, S. J., Moran, R. A., Swindells, J. & McNally, A., 13 Jun 2022, In: Microbial Genomics. 8, 6, 11 p., 000841.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Whole Genome Sequencing 100%
  • Klebsiella oxytoca 32%
  • galantide 30%
  • Enterobacter cloacae 28%
  • Neonatal Screening 25%
  36 Downloads (Pure)
• 2021

  Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

  The COVID-19 Genomics UK (COG-UK) Consortium & McNally, A., 13 May 2021, In: Nature. 593, 7858, p. 266–269 4 p.

  Research output: Contribution to journal › Article › peer-review

  • SARS Virus 100%
  • England 67%
  • Genes 27%
  • Reproduction 26%
  • Age Groups 9%
  22 Citations (Scopus)

• Carbapenem and colistin resistance in Enterobacter: determinants and clones

  Zong, Z., Feng, Y. & McNally, A., Jun 2021, In: Trends in Microbiology. 29, 6, p. 473-476 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterobacter 100%
  • Colistin 99%
  • Carbapenems 90%
  • Clone Cells 61%
  • Pressure 16%

• Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

  COVID-19 Genomics UK (COG-UK) Consortium, May 2021, In: The Lancet. Public health. 6, 5, p. e335-e345 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • England 53%
  • Infections 32%
  • Natural Science Disciplines 19%
  • National Institutes of Health (U.S.) 14%
  8 Citations (Scopus)

  162 Downloads (Pure)

• Dynamics of intestinal multidrug-resistant bacteria colonisation contracted by visitors to a high-endemic setting: a prospective, daily, real-time sampling study

  Kantele, A., Kuenzli, E., Dunn, S. J., Dance, D. A. B., Newton, P. N., Davong, V., Mero, S., Pakkanen, S. H., Neumayr, A., Hatz, C., Snaith, A., Kallonen, T., Corander, J. & McNally, A., Apr 2021, In: The Lancet. Microbe. 2, 4, p. e151-e158 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sampling Studies 100%
  • Gram-Negative Bacteria 65%
  • Income 64%
  • Bacteria 52%
  • Laos 38%
  135 Downloads (Pure)

• Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study

  Gladstone, R. A., McNally, A., Pöntinen, A. K., Tonkin-Hill, G., Lees, J. A., Skytén, K., Cléon, F., Christensen, M. O. K., Haldorsen, B. C., Bye, K. K., Gammelsrud, K. W., Hjetland, R., Kümmel, A., Larsen, H. E., Lindemann, P. C., Löhr, I. H., Marvik, Å., Nilsen, E., Noer, M. T., Simonsen, G. S., & 9 othersSteinbakk, M., Tofteland, S., Vattøy, M., Bentley, S. D., Croucher, N. J., Parkhill, J., Johnsen, P. J., Samuelsen, Ø. & Corander, J., Jul 2021, In: The Lancet Microbe. 2, 7, p. e331-e341 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Metagenomics 100%
  • Norway 87%
  • Population Density 69%
  • Escherichia coli 56%
  • Clone Cells 48%
  221 Downloads (Pure)

• Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant

  COVID-19 Genomics UK (COG-UK) Consortium, Elliott, P., Haw, D., Wang, H., Eales, O., Walters, C. E., Ainslie, K. E. C., Atchison, C., Fronterre, C., Diggle, P. J., Page, A. J., Trotter, A. J., Prosolek, S. J., Ashby, D., Donnelly, C. A., Barclay, W., Taylor, G., Cooke, G., Ward, H., Darzi, A., & 3 othersRiley, S., McNally, A. & Beggs, A., 2 Nov 2021, (E-pub ahead of print) In: Science. 18 p., eabl9551.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • England 67%
  • Vaccines 50%
  • Growth 34%
  • Infections 32%
  61 Downloads (Pure)

• Gene-gene relationships in an Escherichia coli accessory genome are linked to function and mobility

  Hall, R. J., Whelan, F. J., Cummins, E. A., Connor, C., McNally, A. & McInerney, J. O., 9 Sept 2021, In: Microbial Genomics. 7, 9, 11 p., 000650.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Escherichia coli 100%
  • Genome 96%
  • Genes 57%
  • Interspersed Repetitive Sequences 22%
  • Gene Regulatory Networks 17%
  93 Downloads (Pure)

• Genomic reconstruction of the SARS-CoV-2 epidemic in England

  Wellcome Sanger Institute COVID-19 Surveillance Team, COVID-19 Genomics UK (COG-UK) Consortium & McNally, A., 16 Dec 2021, In: Nature. 600, 7889, p. 506-511 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • England 77%
  • Epidemics 66%
  • Genomics 39%
  12 Downloads (Pure)

• Limited and strain-specific transcriptional and growth responses to acquisition of a multidrug resistance plasmid in genetically diverse Escherichia coli lineages

  Dunn, S., Carrilero, L., Brockhurst, M. & McNally, A., 27 Apr 2021, In: mSystems. 6, 2, 14 p., e00083-21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Multiple Drug Resistance 100%
  • Plasmids 77%
  • Escherichia coli 67%
  • Growth 48%
  • Interspersed Repetitive Sequences 16%
  229 Downloads (Pure)

• Mapping gene-by-gene single-nucleotide variation in 8,535 Mycobacterium tuberculosis genomes: a resource to support potential vaccine and drug development

  Papakonstantinou, D., Dunn, S. J., Draper, S. J., Cunningham, A. F., O’Shea, M. K., McNally, A. & Achkar, J. M. (ed.), 10 Mar 2021, In: mSphere. 6, 2, 15 p., e01224-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chromosome Mapping 100%
  • Mycobacterium tuberculosis 79%
  • Drug Development 77%
  • Nucleotides 65%
  • Vaccines 61%
  295 Downloads (Pure)

• Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

  The COVID-19 Genomics UK (COG-UK) Consortium, Meng, B., Kemp, S. A., Papa, G., Datir, R., Ferreira, I. A. T. M., Marelli, S., Harvey, W. T., Lytras, S., Mohamed, A., Gallo, G., Thakur, N., Collier, D. A., Mlcochova, P., Duncan, L. M., Carabelli, A. M., Kenyon, J. C., Lever, A. M., De Marco, A., Saliba, C., & 9 othersCulap, K., Cameroni, E., Matheson, N. J., Piccoli, L., Corti, D., James, L. C., Robertson, D. L., Bailey, D. & Gupta, R. K., 29 Jun 2021, In: Cell Reports. 35, 13, 24 p., 109292.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • V 70 100%
  • Severe Acute Respiratory Syndrome 73%
  • Coronavirus 71%
  • Mutation 48%
  • Kd 21%
  64 Citations (Scopus)

  234 Downloads (Pure)

• Spread of carbapenem-resistant Klebsiella pneumoniae in an intensive care unit: a whole-genome sequence-based prospective observational study

  Wei, L., Wu, L., Wen, H., Feng, Y., Zhu, S., Liu, Y., Tang, L., Doughty, E., van Schaik, W., McNally, A. & Zong, Z., 31 Aug 2021, In: Microbiology spectrum. 9, 1, p. 1-12 e00058-21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • carbapenems 100%
  • pneumonia 96%
  • observational studies 95%
  • Carbapenems 86%
  • Klebsiella pneumoniae 84%
  155 Downloads (Pure)

• S-variant SARS-CoV-2 lineage B1.1.7 is associated with significantly higher viral loads in samples tested by ThermoFisher TaqPath RT-qPCR

  Kidd, M., Richter, A., Best, A., Cumley, N., Mirza, J., Percival, B., Mayhew, M., Megram, O., Ashford, F., White, T., Moles-Garcia, E., Crawford, L., Bosworth, A., Atabani, SF., Plant, T. & McNally, A., 13 Feb 2021, (E-pub ahead of print) In: The Journal of Infectious Diseases.

  Research output: Contribution to journal › Article › peer-review

  • SARS Virus 100%
  • Viral Load 65%
  • Mutation 18%
  • Genes 13%

• The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

  COVID-19 Genomics UK (COG-UK) Consortium & ISARIC4C Investigators, 19 Nov 2021, In: iScience. 24, 11, 15 p., 103353.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SARS Virus 100%
  • Epitopes 58%
  • Nucleocapsid 53%
  • T-Lymphocytes 41%
  • Mutation 37%
  20 Downloads (Pure)

• The role of potentiating mutations in the evolution of pandemic Escherichia coli clones

  Cummins, E. A., Snaith, A. E., McNally, A. & Hall, R. J., 17 Nov 2021, (E-pub ahead of print) In: European Journal of Clinical Microbiology & Infectious Diseases. 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Pandemics 100%
  • Clone Cells 74%
  • Escherichia coli 65%
  • Mutation 52%
  • Multiple Drug Resistance 24%
  39 Downloads (Pure)