Metabolism and Systems Research

Research output

Research output per year 1989 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 4104 Article
• 427 Review article
• 422 Abstract
• 110 Chapter
• 490 More
  • 94 Paper
  • 69 Editorial
  • 61 Letter
  • 50 Comment/debate
  • 44 Conference contribution
  • 42 Book
  • 41 Other contribution
  • 21 Chapter (peer-reviewed)
  • 19 Preprint
  • 12 Poster
  • 8 Patent
  • 7 Web publication/site
  • 4 Short survey
  • 4 Doctoral Thesis
  • 3 Book/Film/Article review
  • 2 Entry for encyclopedia/dictionary
  • 2 Other
  • 2 Conference article
  • 2 Working paper
  • 1 Commissioned report
  • 1 Special issue
  • 1 Software

Research output per year

Research output per year

Search results

• 2011

  Biochemistry and physiology of hexose-6-phosphate knockout mice

  Zielinska, A., Walker, E., Stewart, P. & Lavery, G., 1 Apr 2011, p. 213-218. 6 p.

  Research output: Contribution to conference (unpublished) › Paper
  11 Citations (Scopus)

• PTTG-Binding Factor (PBF) induces goitrogenesis and represses iodide uptake in vivo

  Read, M., Lewy, G., Sharma, N., Fong, J., Smith, V., Ryan, GA., Seed, RI., Kwan, PPK., Leadbeater, W., Warfield, A., Knauf, JA., Watkinson, J., Franklyn, J., Boelaert, K. & McCabe, C., 1 Jan 2011.

  Research output: Contribution to conference (unpublished) › Paper
• 2010

  Akt activation in a murine thyroid goitre model induced by the tumourigenic factor PBF

  Read, M., Lewy, G., Sharma, N., Fong, J., Smith, V., Seed, RI., Kwan, P., Leadbeater, W., Warfield, A., Watkinson, J., Franklyn, J., Boelaert, K. & McCabe, C., 1 Jan 2010.

  Research output: Contribution to conference (unpublished) › Paper

• N-terminal pro-brain-type natriuretic peptide: a biochemical surrogate of cardiac function in the potential heart donor

  Dronavalli, V., Ranasinghe, A., Venkateswaran, R., James, SR., McCabe, C., Wilson, IC., Mascaro, JG. & Bonser, R., 1 Aug 2010.

  Research output: Contribution to conference (unpublished) › Paper
• 2009

  A role for PTTG binding factor (PBF) in goitrogenesis

  Read, M., Lewy, G., Fong, J., Smith, V., Seed, RI., Watkins, RJ., Warfield, A., Leadbeater, W., Watkinson, J., Franklyn, J., Boelaert, K. & McCabe, C., 1 Jan 2009.

  Research output: Contribution to conference (unpublished) › Paper

• Enlargement of the thyroid gland in a heterozygous PBF knock-in transgenic mouse model

  Read, M., Fong, J., Lewy, G., Smith, V., Turnell, A., Watkins, RJ., Seed, R., Stewart, S., Warfield, A., Leadbeater, W., Kim, D., Watkinson, J., Franklyn, J., Boelaert, K. & McCabe, C., 1 Jan 2009, p. 371. 1 p.

  Research output: Contribution to conference (unpublished) › Paper

• Evidence of a role for the PTTG binding protein (PBF) in goitrogenesis

  Read, M., Lewy, G., Fong, J., Smith, V., Seed, RI., Watkins, RJ., Leadbeater, W., Watkinson, J., Franklyn, J., Boelaert, K. & McCabe, C., 1 Jan 2009.

  Research output: Contribution to conference (unpublished) › Paper

• Prospective evaluation of the effect of weight loss on intracranial pressure in idiopathic intracranial hypertension

  Sinclair, A., Burdon, M., Ball, A., Nightingale, P., Good, P., Matthews, T., Jacks, A., Lawden, M., Clarke, C., Walker, E., Tomlinson, J., Stewart, P. & Rauz, S., 1 Jan 2009.

  Research output: Contribution to conference (unpublished) › Paper
• 2008

  Adipose cell-adrenal interactions: current knowledge and future perspectives

  Ronconi, V., Turchi, F., Bujalska, I., Giacchetti, G. & Boscaro, M., 1 Apr 2008, p. 100-103. 4 p.

  Research output: Contribution to conference (unpublished) › Paper
  16 Citations (Scopus)

• Initial results from a prototype large (2m) ring PET scanner

  Parker, D. & Ahasan, M., 1 Jan 2008, p. 676-681. 6 p.

  Research output: Contribution to conference (unpublished) › Paper
• 2007

  Cytokine profiles in idiopathic intracranial hypertension

  Ball, A., Sinclair, AJ., Curnow, S., Tomlinson, J., Burdon, M., Walker, E., Stewart, P., Nightingale, P., Clarke, C. & Rauz, S., 1 Jan 2007.

  Research output: Contribution to conference (unpublished) › Paper

• Cytokine profiles in idiopathic intracranial hypertension: a comparison with other neuro-opthalmological conditions

  Ball, A., Sinclair, A., Curnow, S., Tomlinson, J., Walker, E., Clarke, C. & Rauz, S., 1 Jan 2007.

  Research output: Contribution to conference (unpublished) › Paper

• Delayed initiation of subcutaneous insulin therapy after failure of oral glucose-lowering agents in patients with Type 2 diabetes: a population-based analysis in the UK

  Rubino, A., McQuay, LJ., Gough, S., Kvasz, M. & Tennis, P., 1 Dec 2007, p. 1412-1418. 7 p.

  Research output: Contribution to conference (unpublished) › Paper
  109 Citations (Scopus)

• DHEA: why, when, and how much - DHEA replacement in adrenal insufficiency

  Allolio, B., Arlt, W. & Hahner, S., 1 Sept 2007, p. 268-273. 6 p.

  Research output: Contribution to conference (unpublished) › Paper
  19 Citations (Scopus)

• Variation in the Surfactant Protein B gene is associated with development of emphysema in AATD

  Turner, A., Simmonds, M., Newby, P., Gough, S. & Stockley, R., 1 Dec 2007, p. A119.

  Research output: Contribution to conference (unpublished) › Paper
• 2006

  Genetics and mainstream medicine - the importance of two way traffic. Lessons from management review of Osteogenesis Imperfecta (OI) and Congenital Adrenal Hyperlasia (cAH)

  Cole, T., Sleightholme, H., Burgess, L., Glennister, LBJ., Glennister, LBJ., Glennis, R., Arlt, W. & Gittoes, N., 1 Jan 2006.

  Research output: Contribution to conference (unpublished) › Paper

• Molecular genetic investigation into the role of TP53 tumour suppressor gene in the aetiology of second soft tissue sarcomas

  Jenkinson, H., Hawkins, M., Stevens, MCG. & Maher, E., 1 Jun 2006.

  Research output: Contribution to conference (unpublished) › Paper
• 2005

  An apparent defect in the DHEA-DHEAS shuttle defines a novel cause of Polycystic Ovary Syndrome

  Arlt, W., Hammer, F., Filko, D., Chalder, S., Hughes, B., Schofl, C. & Stewart, P., 1 Jan 2005, p. 1-381. 381 p.

  Research output: Contribution to conference (unpublished) › Paper

• Association between serum TSH concentrations and occurrence of atrial fibrillation in a large community-based population of elderly subjects

  Hobbs, F., Parle, J., Roberts, L., Wilson, S., Holder, R., Franklyn, J. & Gammage, M., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• Characterization of a further 11 families with P450 oxidoreductase deficiency - the second most common cause of congenital adrenal hyperplasia

  Arlt, W., Dhir, V., Ivison, H., Marcos, J., Walker, E., Hammer, F., Wudy, SA., Taylor, NF., Malunowicz, EM., Stewart, P. & Shackleton, C., 1 Jan 2005, p. OR34-35.

  Research output: Contribution to conference (unpublished) › Paper

• Characterization of a further 11 families with P450 oxidoreductase deficiency - the second most common cause of congenital adrenal hyperplasia?

  Dhir, V., Ivison, H., Radford, H., Marcos, J., Hammer, F., Walker, E., Stewart, P., Shackleton, C. & Arlt, W., 1 Jan 2005, p. OR 7-2.

  Research output: Contribution to conference (unpublished) › Paper

• How does glucose-insulin-potassium improve haemodynamic performance? Evidence for beta-adrenoreceptor and sarcoplasmic reticulum calcium ATPase up-regulation

  Ranasinghe, A., Quinn, DW., McCabe, C., Pagano, D., Franklyn, J. & Bonser, R., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• No Evidence for DHEA Deficiency in Severe Sepsis - A Stress Paradigm Revisited

  Arlt, W., Hammer, F., Sanning, P., Allolio, B., Stewart, P. & Annane, D., 1 Jan 2005, p. 3-430. 428 p.

  Research output: Contribution to conference (unpublished) › Paper

• P450 oxidoreductase: the cause of Antley-Bixler syndrome and apparent combined steroid 17- and 21-hydroxylase deficiency

  Shackleton, C., Marcos, J., Ivison, H., Dhir, V., Hauffa, BP., Malunowicz, EM., Stewart, P. & Arlt, W., 1 Jan 2005, p. P2-345.

  Research output: Contribution to conference (unpublished) › Paper

• Pituitary tumor transforming gene (PTTG) and genetic instability in thyroid cancers

  Kim, D., Franklyn, J., Smith, V., Stratford, A., Lopes, V., Pemberton, H., Watkinson, J. & McCabe, C., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• PTTG and PBF in human placenta: the effects of intra-uterine growth restriction

  Boelaert, K., Pemberton, H., Bulmer, JN., McCabe, C., Franklyn, J. & Kilby, M., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• PTTG Induces Genomic Instability in Thyroid Cells

  Kim, D., Boelaert, K., Pemberton, H., Stratford, A., Watkinson, J., Franklyn, J. & McCabe, C., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• Quantifying the association between sub-clinical thyroid disease and disorders of mood and cognition

  Roberts, L., Holder, R., Pattison, HM., Franklyn, J., Wilson, S., Hobbs, F. & Parle, J., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• Separase and Securin; Their Roles in the Developing Human Fetal Brain

  Pemberton, H., Boelaert, K., Kilby, M., Franklyn, J. & McCabe, C., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• Subclinical Thyroid Disease - Is Cognition or Mood Affected?

  Roberts, L., Holder, R., Pattison, HM., Franklyn, J., Wilson, S., Hobbs, F. & Parle, J., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper

• The adrenal stress paradigm revisited - a case for DHEA replacement in severe sepsis

  Arlt, W., Hammer, F., Sanning, P., Allolio, B., Stewart, P. & Annane, D., 1 Jan 2005, p. OR 10-6.

  Research output: Contribution to conference (unpublished) › Paper

• The Birmingham Elderly Thyroid Study: Prevalence of sub-clinical thyroid dysfunction

  Wilson, S., Roberts, L., Roalfe, A., Franklyn, J., Hobbs, F. & Parle, J., 1 Jan 2005.

  Research output: Contribution to conference (unpublished) › Paper
• 2004

  Cushing's syndrome due to a metastatic gastrointestinal carcinoid tumour

  Palin, S., Stewart, S., McGregor, EJ., Gittoes, N. & Stewart, P., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Diabetes: obstacles in adherence to treatment (Foreword)

  Barnett, A. & Barnett, A., 1 Jan 2004, p. T1-T2.

  Research output: Contribution to conference (unpublished) › Paper

• Diagnosis of P450 oxidoreductase deficiency (ORD) by steroid analysis

  Shackleton, C., Marcos, J., Adachi, M., Malunowicz, EM., Hauffa, BP. & Arlt, W., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Growth and Development in Two Siblings with P450 Oxidoreductase Deficiency (ORD) - a New Disorder of Steroid Biosynthesis

  Hauffa, BP., Sippell, WG., Shackleton, C. & Arlt, W., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Hexose-6-phosphate dehydrogenase crucially regulates 11beta-hydroxysteroid dehydrogenase type 1 oxoreductase activity - evidence from bacterial and yeast co-expression studies

  Walker, E., Schneider, S., Walker, O., Arlt, W. & Stewart, P., 1 Jan 2004, p. OR39-3.

  Research output: Contribution to conference (unpublished) › Paper

• Interaction of Enteropathogenic Escherichia coli with human intestinal mucosa: role of adhesins and type III secretion

  Shaw, R., Knutton, S., Murphy, M., Cleary, J. & Donnenberg, MS., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Lack of hepatic conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA

  Hammer, F., Subtil, S., Sanning, P., Filko, D., Lux, P., Allolio, B. & Arlt, W., 1 Jan 2004, p. 759-760. 2 p.

  Research output: Contribution to conference (unpublished) › Paper

• No evidence for hepatic conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA - in vivo and in vitro studies

  Hammer, F., Subtil, S., Sanning, P., Filko, D., Lux, P., Allolio, B. & Arlt, W., 1 Jan 2004, p. OR30-6.

  Research output: Contribution to conference (unpublished) › Paper

• Oxidoreductase deficiency (ORD) defines a new variant of congenital adrenal hyperplasia

  Arlt, W., Walker, E., Draper, N., Ivison, H., Ride, J., Hammer, F., Chalder, S., Borucka-Mankiewicz, M., Hauffa, BP., M Malunowicz, E., M Stewart, P. & H L Shackleton, C., 1 Jan 2004, p. OR42-1.

  Research output: Contribution to conference (unpublished) › Paper

• PTTG expression and genomic instability in differentiated thyroid cancer using the FISSR-PCR technique

  Kim, D., McCabe, C., Boelaert, K., Pemberton, H., Stratford, A., Watkinson, J. & Franklyn, J., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• PTTG regulates the associated molecule with the SH3 domain of STAM (AMSH) via its C-terminal PXXP motif

  Gokce, C., Tannahill, L., Stratford, A., Khanim, F., Pemberton, H., Kim, D., Gittoes, N., Boelaert, K., McCabe, C. & Franklyn, J., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Relationship between PTTG expression and genomic instability in differentiated thyroid cancers

  Kim, D., Boelaert, K., Stratford, A., Watkinson, J., Franklyn, J. & McCabe, C., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• Simple clinical and biochemical parameters predict thyroid neoplasia and malignancy in 1500 patients investigated by FNAB

  Boelaert, K., Horacek, J., Daykin, J., Holder, R., Sheppard, M. & Franklyn, J., 1 Jan 2004.

  Research output: Contribution to conference (unpublished) › Paper

• The role of hypoxia and endotoxin in a piglet model of advanced necrotising enterocolitis

  Dhillon, A., Al-Salti, W., Marshall, J., Lander, A., Booth, I. & Ewer, A., 1 Jan 2004, p. A33.

  Research output: Contribution to conference (unpublished) › Paper

• Treating to goal: challenges of current management

  Barnett, A. & Barnett, A., 1 Jan 2004, p. T3-T7.

  Research output: Contribution to conference (unpublished) › Paper

  43 Citations (Scopus)
• 2003

  A piglet model of advanced necrotising enterocolitis following exposure to hypoxia and endotoxin

  Dhillon, AS., Al-Sahti, W., Marshall, J., Ramani, P., Lander, A., Booth, I. & Ewer, A., 1 Jan 2003, p. 73-74. 2 p.

  Research output: Contribution to conference (unpublished) › Paper

• A piglet model of severe necrotising enterocolitis following exposure to hypoxia and endotoxin

  Dhillon, AS., Al-Salti, W., Marshall, J., Ramani, P., Lander, A., Booth, I. & Ewer, A., 1 Jan 2003, p. 570. 1 p.

  Research output: Contribution to conference (unpublished) › Paper

• Enhanced androstenediol generation and increased androgen synthesis in human peripheral blood mononuclear cells with aging - an endocrine link to immunoesenescence?

  Arlt, W., Drescher, D., Subtil, S., Allolio, B. & Hammer, F., 1 Jan 2003, p. 1-333. 333 p.

  Research output: Contribution to conference (unpublished) › Paper