Metabolism and Systems Research

Projects

Projects per year 1992 2007 2008 2009 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2029

• 5 Not started
• 94 Active
• 576 Finished

Projects per year

Search results

• Military Traumatic Brain Injury Biomarker Study, a prospective cohort biomarker study of military and civilian participants with mTBI

  Lucas, S., Karavitaki, N., Bagshaw, A., Sinclair, A., Morris, K., Deeks, J., Blanch, R., Fernandez-Espejo, D., Upthegrove, R., Terry, J., Jensen, O., Belli, T., Sitch, A., Jenkinson, N., Mullinger, K., Dehghani, H., Smith, D., Mazaheri, A., Berhane, S. & Ottridge, R.

  MINISTRY OF DEFENCE

  1/12/21 → 30/11/29

  Project: Other Government Departments

• C-Safe: Improving maternal and perinatal outcomes through safe and appropriate caesarean sections in low- and middle-income countries

  Jones, L., Lilford, R., Hemming, K., Coomarasamy, A. & Thangaratinam, S.

  Medical Research Council

  21/11/22 → 20/11/27

  Project: Research Councils

• Deciphering the complexities in ghrelin receptor signalling to improve understanding of appetite regulation

  Gorvin, C.

  THE WELLCOME TRUST

  1/08/22 → 31/07/27

  Project: Research

• Intervention to Preserve Vision in Idiopathic Intracranial Hypertension: Evaluation of Clinical Effectiveness and Cost Effectiveness

  Sinclair, A., Frew, E., Watts, C., Bach, S. & Brock, K.

  NIHR

  1/09/21 → 28/02/27

  Project: Other Government Departments

• Seizures and the Brain: The Role of Perturbed Dynamic Networks

  Terry, J.

  ENGINEERING & PHYSICAL SCIENCE RESEARCH COUNCIL

  1/08/21 → 31/07/26

  Project: Research Councils

• Sinclair SJT 2019 Defining new treatment and headache mechanisms in raised intracranial ressure

  Brock, K., Sinclair, A. & Barton, D.

  SIR JULES THORN CHARITABLE TRUST

  1/12/20 → 30/06/26

  Project: Research

• Rescue Cervical Cerclage to prevent miscarriage and preterm birth a Randomised Controlled Trial (C-STICH2)

  Brocklehurst, P., Morton, V., Middleton, L., Coomarasamy, A., Morris, K., Jones, L. & Thangaratinam, S.

  NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE

  1/07/18 → 30/04/26

  Project: Other Government Departments

• Generation of beta cells from stems cells using novel regulators

  Akerman, I.

  DIABETES UK

  1/05/21 → 31/10/25

  Project: Research

• EPSRC Network+: Neurotechnology for enabling community-based diagnosis and care

  Sinclair, A. & Terry, J.

  ENGINEERING & PHYSICAL SCIENCE RESEARCH COUNCIL

  1/09/22 → 31/08/25

  Project: Research Councils

• Novel Biomarker Test with Treatment, to Predict and Prevent Miscarriage and Adverse Birth Outcomes in Ethnically Diverse Patient Populations

  Thangaratinam, S. & Morris, K.

  TECHNOLOGY STRATEGY BOARD

  1/04/22 → 31/03/25

  Project: Other Government Departments

• Calcium Supplementation for Prevention of Pre-eclampsia in High Risk Women: CaPE Trial

  Middleton, L., Ewer, A., Moore, P. & Brocklehurst, P.

  NIHR

  1/09/20 → 1/02/25

  Project: Other Government Departments

• Determining how glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP1) synergistically regulate beta cell function

  Hodson, D.

  Medical Research Council

  3/01/22 → 2/01/25

  Project: Research Councils

• Progestogens for preventing miscarriage: a network meta analysis

  Devall, A.

  NIHR

  1/02/21 → 1/01/25

  Project: Research

• Perinatal and 2 year neurodevelopmental outcome in late preterm fetal compromise: the TRUFFLE 2 randomised trial

  Kilby, M.

  NIHR

  1/12/20 → 1/12/24

  Project: Other Government Departments

• HiPP - Centre of Research Excellence in Health in Preconception and Pregnancy: Prevention of maternal obesity

  Thangaratinam, S.

  NATIONAL HEALTH & MEDICAL RESEARCH COUNCIL (NHMRC)

  1/11/19 → 31/10/24

  Project: Research

• Identifying new drug targets for Acute Lymphoblastic Leukaemia in adults through in vitro modelling of lipid metabolism in the tumour microenvironment(s)

  Tennant, D.

  Cancer Research UK

  1/10/21 → 30/09/24

  Project: Research

• Making Radioiodine Treatment a Realistic Therapeutic Opportunity in Breast Cancer

  McCabe, C.

  US ARMY

  30/09/21 → 29/09/24

  Project: Research

• HWB-NMR: a national resource for biomolecular research

  Tennant, D., Young, S., Lavery, G., Peet, A., Ludwig, C., Futterer, K., Guenther, U., Henderson, I., Willcox, B., Adams, D. & Carlomagno, T.

  THE WELLCOME TRUST

  25/09/17 → 25/09/24

  Project: Research

  • Nuclear magnetic resonance 100%
  • NMR Spectrum 72%
  • Sampling 69%
  • Metabolic 67%
  • Fluxes 67%

• PBF Signalling in the Regulation of Cell Motility

  Smith, V.

  BIOTECHNOLOGY & BIOLOGICAL SCIENCES

  1/06/21 → 12/09/24

  Project: Research Councils

• Digital Healthcare: A vehicle for capacity building in ICT skills and public engagement

  Terry, J.

  ENGINEERING & PHYSICAL SCIENCE RESEARCH COUNCIL

  1/09/22 → 31/08/24

  Project: Research Councils

• Multimorbidity in Pregnancy: Determinant, Consequences, Clusters and Trajectories

  Brocklehurst, P., Nirantharakumar, K., Thangaratinam, S. & Taylor, B.

  Medical Research Council

  1/09/21 → 31/08/24

  Project: Research Councils

• The role of the G protein-coupled receptor, LGR4, in bone metabolism and obesity

  Gorvin, C.

  Novo Nordisk Fonden

  1/09/19 → 31/08/24

  Project: EU

• Mechanisms and therapeutics for headache in Idiopathic Intracranial Hypertension

  Yiangou, A. & Sinclair, A.

  Association of British Neurologists

  4/08/21 → 3/08/24

  Project: Research

• Quantifying the effect of AEDs and surgery using non-invasive recordings and computational modelling

  Woldman, W.

  Epilepsy Research UK

  1/07/20 → 30/06/24

  Project: Research

• Interrogating hypoxic control of CD4 and CD8 T cell function in the tumour microenvironment

  Tennant, D. & Dimeloe, S.

  Cancer Research UK

  1/06/21 → 31/05/24

  Project: Research

• Interrogating nicotinamide riboside kinase activity as a key determinant of CD4+ T cell metabolism, fate and function

  Lavery, G. & Dimeloe, S.

  Medical Research Council

  1/04/21 → 31/03/24

  Project: Research Councils

• Towards a Single-Molecule Pharmacology of G-Protein-Coupled Receptors: Understanding Receptor Dynamics to Develop Innovative Drugs

  Calebiro, D.

  THE WELLCOME TRUST

  12/03/19 → 12/03/24

  Project: Research

  • metabotropic glutamate receptor 4 100%
  • Metabotropic Glutamate Receptors 74%
  • trajectories 46%
  • trapping 45%
  • Synaptic Transmission 41%

• Direct-to-consumer genetic testing and donor-conception: support and governance in emerging digital systems

  Kirkman-Brown, J.

  ECONOMIC & SOCIAL RESEARCH COUNCIL

  1/03/21 → 29/02/24

  Project: Research

• Pseudohypoxia-led identification of metabolic vulnerabilities in hypoxic tumours to improve patient outcomes

  Tennant, D., Ludwig, C. & Spill, F.

  Cancer Research UK

  1/02/18 → 31/01/24

  Project: Research

  • Pyrroline Carboxylate Reductases 100%
  • delta-1-pyrroline-5-carboxylate 94%
  • Pyrroline 75%
  • Tricarboxylic Acid 68%
  • Citric Acid Cycle 65%

• COVID-19 in pregnant women: Living Systematic Reviews on prevalence, presentation, prognosis, diagnosis and treatment

  Thangaratinam, S. & Allotey, J.

  WORLD HEALTH ORGANISATION

  20/05/20 → 31/12/23

  Project: Research

• Thermal Therapy For ACC

  Taylor, A. & Arlt, W.

  National University of Ireland, Galway

  1/11/21 → 31/10/23

  Project: Research

• Using lactate testing to improve maternal sepsis identification: a multi-country test accuracy study and feasibility assessment

  Gallos, I., Coomarasamy, A., Devall, A. & Deeks, J.

  Medical Research Council

  1/01/21 → 30/09/23

  Project: Research Councils

• NIHR Global Health Research unit- JAN 2017 - OPEN FOR DISSEMINATION COSTS ONLY

  Lissauer, D., Sundar, S., Brocklehurst, P., Roberts, T., Pinkney, T., Morton, D. & Bhangu, A.

  NIHR CENTRAL COMMISSIONING FACILITY

  1/07/17 → 30/09/23

  Project: Other Government Departments

• Miscarriage and Global Health Research

  Coomarasamy, A.

  BIRMINGHAM WOMENS NHS TRUST

  1/06/16 → 30/09/23

  Project: Research

• Miscarriage and Global Health Research

  Coomarasamy, A. & Kirkman-Brown, J.

  BIRMINGHAM WOMENS NHS TRUST

  1/06/16 → 30/09/23

  Project: Research

• Dissecting and leveraging glucagon-like peptide-1 brain pathways in obesity

  Hodson, D.

  EUROPEAN COMMISSION

  1/09/21 → 31/08/23

  Project: EU

• Effectiveness of progesterone to prevent miscarriage in women with early pr

  Coomarasamy, A.

  BIRMINGHAM WOMEN'S CHARITABLE FUNDS

  1/09/18 → 31/08/23

  Project: Research

• Altering pancreatic beta cell fate through novel regulators

  Akerman, I.

  THE ACADEMY OF MEDICAL SCIENCES

  1/09/21 → 31/08/23

  Project: Research

• Can new drug approaches elicit a novel dual action of radioiodine treatment?

  McCabe, C.

  BRITISH THYROID FOUNDATION

  1/09/21 → 30/08/23

  Project: Research

• Unlocking cortisol activation in muscle as a treatable cause of muscle wasting in kidney failure

  Hardy, R.

  Medical Research Council

  4/08/20 → 3/08/23

  Project: Research Councils

• An International Collaboration to Implement and Evaluate at Scale the Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis Programme)

  Gallos, I., Roberts, T., Hemming, K., Coomarasamy, A., Martin, J. & Devall, A.

  Medical Research Council

  1/02/21 → 31/07/23

  Project: Research Councils

• Exploratory study of candidate molecular biomarkers in IIH patients

  Sinclair, A.

  MIDLAND NEUROSCIENCE TEACHING & RESEARCH FUND

  1/07/20 → 1/07/23

  Project: Research

• Identifying biomarkers through MicroRNA profiling.

  Sinclair, A.

  MIDLAND NEUROSCIENCE TEACHING & RESEARCH FUND

  1/07/20 → 1/07/23

  Project: Research

• Early detection and treatment of post-partum hemorrhage using the MOTIVE bundle : a World Health Organization cluster randomized trial with health economic analysis (the E-MOTIVE study)

  Devall, A., Hemming, K., Roberts, T., Middleton, L., Brocklehurst, P., Coomarasamy, A., Gallos, I. & Martin, J.

  THE BILL & MELINDA GATES FOUNDATION

  1/11/19 → 30/06/23

  Project: Research

• The role of chain length in fatty acid uptake in both health and disease: a combined experimental theoretical modelling approach

  Thomas, P.

  Medical Research Council

  1/02/20 → 9/06/23

  Project: Research Councils

• Reducing Infant Mortality in the West Midlands

  Goodson, L., Morris, K., Chandan, J., Jolly, K., Taylor, J., Crowe, F., Garstang, J., Damery, S., Nirantharakumar, K., Taylor, B. & Thangaratinam, S.

  CRN: WEST MIDLANDS

  1/06/22 → 31/05/23

  Project: Research

• Effective use of care packages in global maternal health settings (CHAMPION)

  Coomarasamy, A.

  BIRMINGHAM WOMENS NHS TRUST

  1/06/16 → 31/05/23

  Project: Research

• Understanding how sleep is impacted by neurological and neurodevelopmental conditions using personalised brain networks from EEG data

  Junges, L.

  THE WATERLOO FOUNDATION

  1/09/21 → 30/05/23

  Project: Research

• Diet and physical activity in pregnancy to prevent gestational diabetes: Individual Participant Data (IPD) meta-analysis on the differential effects of interventions with economic evaluation

  Thangaratinam, S., Nirantharakumar, K. & Roberts, T.

  NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE

  1/03/21 → 30/04/23

  Project: Other Government Departments

• H2020_GF_OPTIMAL-D

  Hewison, M.

  EUROPEAN COMMISSION

  15/10/19 → 14/04/23

  Project: EU