Institute for Head and Neck Studies and Education

Research output

Research output per year 2009 2015 2016 2018 2019 2020 2021 2024

• 137 Article
• 10 Review article
• 5 Chapter
• 4 Conference contribution
• 13 More
  • 4 Comment/debate
  • 4 Abstract
  • 2 Editorial
  • 2 Letter
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2024

  Assessment of endpoint definitions in recurrent and metastatic mucosal head and neck squamous cell carcinoma trials: HNCIG international consensus recommendations

  Lim, A., Laskar, S., Steuer, C., Chow, V. L. Y., Szturz, P., Henson, C., Day, A. T., Bates, J. E., Lazarakis, S., McDowell, L., Mehanna, H. & Yom, S. S., 26 Jan 2024, (Accepted/In press) In: The Lancet Oncology.

  Research output: Contribution to journal › Article › peer-review

  • Squamous Cell Carcinoma of Head and Neck 100%
  • Clinical Trials 58%
  • Head and Neck Neoplasms 45%
  • Survival 24%

• Clinical trial endpoint use and definitions in curative-intent trials for mucosal head and neck squamous cell carcinomas: HNCIG international consensus recommendations

  Lim, A. M., McDowell, L., Hurt, C., Tourneau, C. L., Homma, A., Shenouda, G., Thompson, D. J., Moya-Plana, A., Henson, C., Szturz, P., Day, A. T., Bates, J. E., Lazarakis, S., Thariat, J., Psyrri, A., Mehanna, H. & Yom, S. S., 26 Jan 2024, (Accepted/In press) In: The Lancet Oncology.

  Research output: Contribution to journal › Article › peer-review

  • Squamous Cell Carcinoma of Head and Neck 100%
  • Stakeholder Participation 66%
  • Clinical Trials 58%
  • Head and Neck Neoplasms 45%
  • Progression-Free Survival 40%

• CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer

  Mehanna, H., Gaunt, P., Kong, A., Hartley, A., Sanghera, P., Forster, M., Sen, M., Paleri, V., Fong, C., Geropantas, D., Srinivasan, D., Garikipati, S., Moleron, R., Casswell, G., Aynsley, E., Ward, A., O'Toole, L., Mirza, A., Firth, C., Humphreys, I., & 2 othersFulton-Lieuw, T. & Nankivell, P., 15 Jan 2024, In: Trials. 25, 50.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oropharyngeal Neoplasms 100%
  • durvalumab 74%
  • Randomized Controlled Trials 50%
  • Health Care Outcome Assessment 21%
  • Progression-Free Survival 19%
  16 Downloads (Pure)

• Criteria for the diagnosis of extra nodal extension detected on radiological imaging in head and neck cancer: HNCIG international consensus recommendations

  Henson, C., Abou-Foul, A., Glastonbury, C., Huang, S. H., King, A. D., Lydiatt, W. M., McDowell, L., Nagelschneider, A. A., Nankivell, P., O'Sullivan, B., Rhys, R., Xiao, Y., Yu, E., Andrew, D., Asmussen, J. T., Bidault, F., Dankbaar, J. W., de Graaf, P., Gebrim, E. S., Hu, C., & 13 othersDing, J., Kanda, T., Kim, J., Kuno, H., Medrano-Martorell, S., Oikonomopoulos, N., Park-Nam Goh, J., Santos-Armentia, E., Schafigh, D. G., Subramaniam, R. M., Wu, X., Yom, S. S. & Mehanna, H., 26 Jan 2024, (Accepted/In press) In: The Lancet Oncology.

  Research output: Contribution to journal › Article › peer-review

  • Head and Neck Neoplasms 100%
  • Extranodal Extension 91%
  • Terminology 66%
  • Radiology 33%
  • Patient Selection 29%

• Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study

  Mehanna, H., Rapozo, D., Zeidler, S. V. V., Harrington, K., Winter, S., Hartley, A., Nankivell, P., Schache, A., Sloan, P., Odell, E., Thavaraj, S., Hunter, K., Shah, K., Thomas, G., Long, A., Amel-Kashipaz, R., Brown, R., Conn, B., Hall, G., Matthews, P., & 15 othersWeir, J., Yeo, Y., Pring, M., West, C., McCaul, J., Golusinski, P., Sitch, A., Spruce, R., Batis, N., Bryant, J., Brooks, J., Jones, T. M., Buffa, F., Haider, S. & Robinson, M., 17 Jan 2024, In: Clinical Cancer Research. 30, 2, p. 356–367

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Squamous Cell Carcinoma 100%
  • Biomarkers 62%
  • Secondary Care Centers 37%
  • Tumor-Infiltrating Lymphocytes 30%
  • Survivin 28%
  1 Downloads (Pure)

• Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database

  Baliga, S., Abou-Foul, A. K., Parente, P., Szturz, P., Thariat, J., Shreenivas, A., Nankivell, P., Bertolini, F., Blau, J., Blakaj, D., Brennan, S., Brunet, A., Bueno De Oliveira, T., Burtness, B., Carral Maseda, A., Chow, V. L-Y., Chua, M. LK., de Ridder, M., Garikipati, S., Hanai, N., & 16 othersHo, F. C. H., Huang, S. H., Kiyota, N., Klinghammer, K., Kowalski, L. P., Kwong, D. L., McDowell, L. J., Merlano, M. C., Nair, S., Economopoulou, P., Overgaard, J., Psyrri, A., Tribius, S., Waldron, J., Yom, S. S. & Mehanna, H., May 2024, In: European Journal of Cancer. 203, 10 p., 114038.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Head and Neck Neoplasms 100%
  • Datasets 78%
  • Clinical Trials 64%
  • Databases 59%
  • Information Dissemination 39%

• Implementing the time-to-event continual reassessment method in the presence of partial orders in a phase I head and neck cancer trial

  Patel, A., Brock, K., Slade, D., Gaunt, C., Kong, A., Mehanna, H., Billingham, L. & Gaunt, P., 13 Jan 2024, In: BMC Medical Research Methodology. 24, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Head and Neck Neoplasms 100%
  • Maximum Tolerated Dose 29%
  • Squamous Cell Carcinoma of Head and Neck 27%
  • Radiotherapy 17%
  • Clinical Trials 16%
  12 Downloads (Pure)

• Results and lessons learnt from the WISTERIA phase I trial combining AZD1775 with cisplatin pre- or post-operatively in head and neck cancer

  Kong, A., Kirkham, A. J., Savage, J. S., Mant, R., Lax, S., Good, J., Forster, M. D., Sacco, J. J., Schipani, S., Harrington, K. J., Yap, C. & Mehanna, H., 29 Jan 2024, In: BJC Reports. 2, 1, 9 p., 6.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • MK-1775 100%
  • Head and Neck Neoplasms 54%
  • Cisplatin 48%
  • Clinical Trials, Phase I 10%
  • Suspensions 7%
  18 Downloads (Pure)

• Standardised definitions and diagnostic criteria for extra nodal extension on histopathological examination in head and neck cancer: HNCIG international consensus recommendations

  Abou-Foul, A., Henson, C., Robinson, M., Chernock, R. D., Huang, S. H., Lydiatt, W. M., Mcdowell, L., O'Sullivan, B., Perez-Ordonez, B., Nankivell, P., Ruiz-Bravo, E., Chiosea, S., McGreen, T. M., Hunter, K. D., Hwang, J. S. G., Koljenovic, S., Koppes, S. A., Larsen, S. R., Lo, A. W., Costes-Martineau, V., & 11 othersMittal, N., Mori, T., Panayiotides, I. G., Pinto, C. A. L., Scheckenbach, K., Seethala, R. R., Ulhøi, B. P., Vingiani, A., Zhang, Y., Yam, S. S. & Mehanna, H., 7 Mar 2024, (Accepted/In press) In: The Lancet Oncology.

  Research output: Contribution to journal › Article › peer-review

  • Extranodal Extension 100%
  • Squamous Cell Carcinoma of Head and Neck 81%
  • Terminology 73%
  • Head and Neck Neoplasms 73%
  • Data Analysis 54%
• 2023

  A systematic review of the effectiveness of patient‐initiated follow‐up after cancer

  Dretzke, J., Chaudri, T., Balaji, R., Mehanna, H., Nankivell, P., Moore, D. J. & the PETNECK2 Research Team, Sept 2023, In: Cancer Medicine. 12, 18, p. 19057-19071 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Systematic Reviews 100%
  • Randomized Controlled Trials 91%
  • Cancer Survivors 74%
  • Melanoma 56%
  • Appointments and Schedules 55%
  17 Downloads (Pure)

• Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial

  Wilson, J. A., O'Hara, J., Fouweather, T., Homer, T., Stocken, D. D., Vale, L., Haighton, C., Rousseau, N., Wilson, R., McSweeney, L., Wilkes, S., Morrison, J., MacKenzie, K., Ah-See, K., Carrie, S., Hopkins, C., Howe, N., Hussain, M., Mehanna, H., Raine, C., & 3 othersSullivan, F., von Wilamowitz-Moellendorff, A. & Teare, M. D., 17 Jun 2023, In: The Lancet. 401, 10393, p. 2051-2059 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tonsillitis 100%
  • Tonsillectomy 96%
  • Conservative Treatment 69%
  • Randomized Controlled Trials 52%
  • Pharyngitis 27%
  2 Citations (Scopus)

  23 Downloads (Pure)

• Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia

  Mahmood, H., Shephard, A., Hankinson, P., Bradburn, M., Araujo, A. L. D., Santos-Silva, A. R., Lopes, M. A., Vargas, P. A., McCombe, K. D., Craig, S. G., James, J., Brooks, J., Nankivell, P., Mehanna, H., Rajpoot, N. & Khurram, S. A., 27 Sept 2023, (E-pub ahead of print) In: British Journal of Cancer.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Recurrence 100%
  • Eosine Yellowish-(YS) 57%
  • Squamous Cell Carcinoma 48%
  • Cytoplasm 47%
  • Epithelial Cells 41%
  9 Downloads (Pure)

• Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping

  Payne, K., Brooks, J., Batis, N., Khan, N., El-Asrag, M., Nankivell, P., Mehanna, H. & Taylor, G., 9 Nov 2023, In: British Journal of Cancer. 129, 10, p. 1590-1598 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Circulating Neoplastic Cells 100%
  • Squamous Cell Carcinoma of Head and Neck 89%
  • Proteomics 74%
  • Epithelial-Mesenchymal Transition 27%
  • Single-Cell Analysis 7%
  29 Downloads (Pure)

• Lead Time to Recurrence After Posttreatment Plasma and Saliva HPV DNA Testing in Patients With Low-Risk HPV Oropharynx Cancer

  Califano, J., Yousef, A., Mostafa, H., Valsamakis, A., Zhang, X., Batis, N., Varghese, C., Parish, J., Forman, M., Jarrett, J., Messer, K. & Mehanna, H., 1 Sept 2023, In: JAMA Otolaryngology - Head and Neck Surgery. 149, 9, p. 812-819 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oropharyngeal Neoplasms 100%
  • Saliva 73%
  • Recurrence 43%
  • DNA 42%
  • Phase III Clinical Trials 20%
  20 Downloads (Pure)

• Patient preference for commonly‐used, head and neck cancer‐specific quality of life questionnaires in the follow‐up setting (Determin): A multi‐centre randomised controlled trial and mixed methods study

  DETERMIN Study Management Group, 12 Jun 2023, In: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. 48, 4, p. 613-622 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Patient Preference 100%
  • Neck 68%
  • Head 65%
  • Randomized Controlled Trials 60%
  • Quality of Life 58%
  22 Downloads (Pure)

• Prognostic Implications of p16 and HPV discordance in oropharyngeal cancer: a multicenter, multinational (HNCIG-EPIC-OPC) individual patient data analysis

  Mehanna, H., Nankivell, P., Batis, N. & Brooks, J., 13 Feb 2023, In: The Lancet Oncology. 24, 3, p. 239-251 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oropharyngeal Neoplasms 100%
  • Data Analysis 56%
  • Disease-Free Survival 13%
  • Survival 10%
  • Immunohistochemistry 9%
  23 Downloads (Pure)

• The efficacy and cost effectiveness of Real Time Ultrasound Elastography in the investigation of thyroid nodules and the diagnosis of thyroid cancer

  Mehanna, H., Nankivell, P., Sharma, N., Boelaert, K., Deeks, J., Madani, G., Woolley, R., Fulton-Lieuw, T., Palmer, A. & Taylor, J., 4 May 2023, (Accepted/In press) In: Health Technology Assessment.

  Research output: Contribution to journal › Article › peer-review

  • Elasticity Imaging Techniques 100%
  • Thyroid Nodule 98%
  • Thyroid Neoplasms 83%
  • cancer 74%
  • Cell Biology 71%

• Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation

  Wilson, J. A., Fouweather, T., Stocken, D. D., Homer, T., Haighton, C., Rousseau, N., O'Hara, J., Vale, L., Wilson, R., Carnell, S., Wilkes, S., Morrison, J., Ah-See, K., Carrie, S., Hopkins, C., Howe, N., Hussain, M., Lindley, L., MacKenzie, K., McSweeney, L., & 6 othersMehanna, H., Raine, C., Whelan, R. S., Sullivan, F., von Wilamowitz-Moellendorff, A. & Teare, D., 8 Dec 2023, In: Health technology assessment (Winchester, England). 27, 31, p. 1-195 195 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tonsillectomy 100%
  • Pharyngitis 94%
  • Conservative Treatment 71%
  • Cost-Benefit Analysis 69%
  • life years 40%
  4 Downloads (Pure)
• 2022

  A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma

  Shaban, M., Raza, S. E. A., Hassan, M., Jamshed, A., Mushtaq, S., Loya, A., Batis, N., Brooks, J., Nankivell, P., Sharma, N., Robinson, M., Mehanna, H., Khurram, S. A. & Rajpoot, N., Feb 2022, In: Journal of Pathology. 256, 2, p. 174-185 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Squamous Cell Carcinoma of Head and Neck 100%
  • Lymphocytes 62%
  • Survival 49%
  • Neoplasms 28%
  • Head and Neck Neoplasms 13%
  32 Downloads (Pure)

• Characterising the epithelial-mesenchymal transition status of circulating tumour cells in head and neck squamous cell carcinoma

  Payne, K., Brooks, J., Batis, N., Taylor, G., Nankivell, P. & Mehanna, H., 5 Aug 2022, In: Head & Neck. 44, 11, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Circulating Neoplastic Cells 100%
  • Squamous Cell Carcinoma of Head and Neck 89%
  • Epithelial-Mesenchymal Transition 83%
  • Microfluidics 19%
  • Flow Cytometry 18%
  34 Downloads (Pure)

• Clinicians’ views of patient-initiated follow-up in head and neck cancer: a qualitative study to inform the PETNECK2 trial

  Lorenc, A., Wells, M., Fulton-Lieuw, T., Nankivell, P., Mehanna, H., Jepson, M., PETNECK2 Research Team & Karwath, A., Apr 2022, In: Clinical Oncology. 34, 4, p. 230-240 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Head and Neck Neoplasms 100%
  • Focus Groups 22%
  • Allied Health Personnel 18%
  • Workload 15%
  • boldenone undecylenate 11%
  36 Downloads (Pure)

• Concordance of p16INK4a and E6*I mRNA among HPV-DNA positive oropharyngeal, laryngeal and oral cavity carcinomas from the ICO international study

  ICO International HPV in Head and Neck Cancer Study Group, 4 Aug 2022, In: Cancers. 14, 15, 12 p., 3787.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mouth 100%
  • Carcinoma 77%
  • Messenger RNA 66%
  • DNA 65%
  • Neck 32%
  14 Downloads (Pure)

• Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries

  NIHR Global Health Research Unit on Global Surgery, COVIDSurg Collaborative, Glasbey, J., Bhangu, A., Davies, J., Nankivell, P. & Li, E., 5 Nov 2022, In: The Lancet. 400, 10363, p. 1607-1617 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Income 100%
  • Pandemics 25%
  • pirmenol 15%
  • Holistic Health 12%
  • Self-Assessment 9%
  21 Downloads (Pure)

• Exploring the views of patients' and their family about patient-initiated follow-up in head and neck cancer: a mixed methods study

  PETNECK2 Research Team, 4 Jul 2022, (E-pub ahead of print) In: European journal of cancer care. 12 p., e13641.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Head and Neck Neoplasms 100%
  • Appointments and Schedules 12%
  • Self-Help Groups 9%
  • Aftercare 8%
  • Self-Management 8%
  26 Downloads (Pure)

• Learning from COVID-19 and planning post-pandemic cities to reduce pathogen transmission pathways

  Andres, L., Bryson, J. R., Mehanna, H. & Moawad, P., 4 Jul 2022, (E-pub ahead of print) In: Town Planning Review. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • pandemics 100%
  • pathogen 69%
  • learning 61%
  • planning 46%
  • city 41%
  71 Downloads (Pure)

• SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

  COVIDSurg Collaborative, GlobalSurg Collaborative, Nankivell, P. & Li, E., Jan 2022, In: Anaesthesia. 77, 1, p. 28-39 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Venous Thromboembolism 73%
  • Cohort Studies 46%
  • Prospective Studies 43%
  • Infections 32%
• 2021

  A cost-utility analysis comparing CT surveillance, PET-CT surveillance, and planned postradiation neck dissection for advanced nodal HPV-positive oropharyngeal cancer

  Fu, T., Scheffler, P., Forner, D., Noel, C., Huang, S. H., Gilbert, R., Goldstein, D., O'Sullivan, B., Mehanna, H., Waldron, J. & de Almeida, J., 1 Jun 2021, (E-pub ahead of print) In: Cancer. 127, 18, p. 3372-3380

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oropharyngeal Neoplasms 100%
  • Neck Dissection 88%
  • Positron Emission Tomography Computed Tomography 82%
  • Cost-Benefit Analysis 65%
  • Tomography 51%
  39 Downloads (Pure)

• Comprehensive genomic and transcriptomic analysis of three synchronous primary tumours and a recurrence from a head and neck cancer patient

  Bresadola, L., Weber, D., Ritzel, C., Lower, M., Bukur, V., Akilli-Öztürk, Ö., Becke, J., Mehanna, H., Schrörs, B., Vascotto, F., Sahin, U. & Kong, A., 15 Jul 2021, In: International Journal of Molecular Sciences. 22, 14, 17 p., 7583.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tumors 100%
  • Head and Neck Neoplasms 98%
  • tumors 93%
  • cancer 91%
  • Alcohols 71%
  146 Downloads (Pure)

• Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic

  STARSurg Collaborative and COVIDSurg Collaborative , Nankivell, P. & Li, E., 1 Dec 2021, In: British Journal of Surgery. 108, 12, p. 1448-1464 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Pandemics 82%
  • Lung 41%
  • Coronavirus Infections 33%
  118 Downloads (Pure)

• Development and validation of an improved classification and risk stratification system for carotid body tumors: a multinational collaborative cohort study

  Mehanna, H., Mistry, P., Golusinski, P., Maio, P. D., Nankivell, P., Snider, F., Ferrante, A. M. R., Montalto, N., Nicolai, P., Marcantoni, A., Grandi, C., Zavatta, M., Grego, F., Malec, K., Hosal, S., Suslu, N., Kuscu, O., Torrealba, I., Valdes, F., Sharma, N., & 6 othersAyuk, J., Monksfield, P., Irving, R., Dunn, J. A., Kay, M. & Borsetto, D., Nov 2021, In: Head and Neck. 43, 11, p. 3448-3458

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carotid Body Tumor 100%
  • Cohort Studies 44%
  • Decision Making 9%
  • Retrospective Studies 7%
  64 Downloads (Pure)

• Differential expression of potential biomarkers of oral squamous cell carcinoma development

  Pansini, P. F., do Valle, I. B., Damasceno, T. C. D., de Abreu, P. M., Có, A. C. G., López, R. V. M., Lenzi, J., Rocha, R. M., Souza, E. D., Curado, M. P., Mehanna, H., Nankivell, P., de Podestá, J. R. V. & von Zeidler, S. V., 11 Apr 2021, (E-pub ahead of print) In: Head and Neck Pathology. 15, 4, p. 1127-1136

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • polo-like kinase 1 100%
  • Survivin 79%
  • Squamous Cell Carcinoma 55%
  • Biomarkers 43%
  • Proto-Oncogene Proteins c-bcl-2 26%
  54 Downloads (Pure)

• Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

  COVIDSurg Collaborative, Sundar, S., Nankivell, P., Morton, D. & Li, E., Nov 2021, In: The Lancet. 22, 11, p. 1507-1517 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pandemics 100%
  • Cohort Studies 64%
  • Prospective Studies 59%
  • Neoplasms 30%
  • Light 18%
  18 Downloads (Pure)

• Human papilloma virus detection in oropharyngeal carcinomas with in situ hybridisation using hand crafted morphological features and deep central attention residual networks

  Fouad, S., Landini, G., Robinson, M., Song, M. & Mehanna, H., Mar 2021, In: Computerized Medical Imaging and Graphics. 88, 11 p., 101853.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Papillomaviridae 100%
  • Viruses 94%
  • Carcinoma in Situ 91%
  • In Situ Hybridization 73%
  • Hand 61%
  27 Downloads (Pure)

• Hypofractionated chemoradiation for head and cancer: data from the PET NECK trial

  Vreugdenhil, M., Fong, C., Sanghera, P., Hartley, A., Dunn, J. & Mehanna, H., Feb 2021, In: Oral Oncology. 113, 6 p., 105112.

  Research output: Contribution to journal › Article › peer-review

  • Head and Neck Neoplasms 100%
  • Pandemics 79%
  • Appointments and Schedules 60%
  • Quality of Life 48%
  • Neck Dissection 29%
  2 Citations (Scopus)

• Improvement in dysphagia outcomes following clinical target volume reduction in the De-ESCALaTE Study

  Vreugdenhil, M., Fong, C., Iqbal, G., Roques, T., Evans, M., Palaniappan, N., Yang, H., O'Toole, L., Sanghera, P., Nutting, C., Foran, B., Sen, M., Al Booz, H., Fulton-Lieuw, T., Dalby, M., Dunn, J., Hartley, A. & Mehanna, H., 30 Jul 2021, (E-pub ahead of print) In: Clinical Oncology. 33, 12, p. 795-803

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Deglutition Disorders 100%
  • Radiotherapy 34%
  • Survival 27%
  • Oropharyngeal Neoplasms 21%
  • Quality of Life 21%
  40 Downloads (Pure)

• Lack of predictive tools for conventional and targeted cancer therapy: barriers to biomarker development and clinical translation

  Batis, N., Brooks, J., Payne, K., Sharma, N., Nankivell, P. & Mehanna, H., Sept 2021, In: Advanced Drug Delivery Reviews. 176, 113854.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biological Marker 100%
  • Biomarkers 72%
  • Neoplasms 35%
  • Potential Barrier 24%
  • Translational Medical Research 20%
  132 Downloads (Pure)

• Methodological approach for determining the minimal important difference and minimal important change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the swallowing scale

  EORTC Quality of Life Group, EORTC Head and Neck Cancer Group, Singer, S., Hammerlid, E., Tomaszewska, I. M., Amdal, C. D., Bjordal, K., Herlofson, B. B., Santos, M., Silva, J. C., Mehanna, H., Fullerton, A., Brannan, C., Gonzalez, L. F., Inhestern, J., Pinto, M., Arraras, J. I., Yarom, N., Bonomo, P., Baumann, I., & 12 othersGalalae, R., Nicolatou-Galitis, O., Kiyota, N., Raber-Durlacher, J., Salem, D., Fabian, A., Boehm, A., Krejovic-Trivic, S., Chie, W-C., Simon, C., Licitra, L. & Sherman, A. C., 16 Jul 2021, (E-pub ahead of print) In: Quality of Life Research.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Deglutition 100%
  • Head and Neck Neoplasms 98%
  • cancer 88%
  • ROC Curve 41%
  • recipient 40%
  106 Downloads (Pure)

• Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic

  COVIDSurg Collaborative, Jan 2021, In: British Journal of Surgery. 108, 1, p. 88-96 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Pandemics 72%
  • Postoperative Complications 58%
  • Minor Surgical Procedures 45%
  • Lung 36%
  10 Citations (Scopus)

• Safety and feasibility of surgery for oropharyngeal cancers during the SARS-CoV-2-pandemic

  Gorphe, P., Grandbastien, B., Dietz, A., Duvvuri, U., Ferris, R., Golusinski, W., Holsinger, F., Hosal, S., Lawson, G., Mehanna, H., Paleri, V., Shaw, R., Succo, G., Rene Leemans, C. & Simon, C., 24 Mar 2021, In: Frontiers in Oncology. 11, 651123.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  115 Downloads (Pure)

• SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

  COVIDSurg Collaborative & GlobalSurg Collaborative, 27 Sept 2021, In: British Journal of Surgery. 108, 9, p. 1056–1063 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Vaccination 54%
  • Cohort Studies 46%
  • Prospective Studies 43%
  • Population 22%
  7 Citations (Scopus)

• The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress

  Gleneadie, H. J., Baker, A. H., Batis, N., Bryant, J., Jiang, Y., Clokie, S. J. H., Mehanna, H., Garcia, P., Gendoo, D. M. A., Roberts, S., Burley, M., Molinolo, A. A., Gutkind, J. S., Scheven, B. A., Cooper, P. R., Parish, J. L., Khanim, F. L. & Wiench, M., 31 Mar 2021, In: Cancer Letters. 501, p. 172-186 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Decitabine 100%
  • Acetaminophen 81%
  • DNA Methylation 76%
  • Analgesics 66%
  • Oxidative Stress 56%
  247 Downloads (Pure)

• The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying-the head and neck cancer model

  Matos, L. L., Forster, C. H. Q., Marta, G. N., Castro Junior, G., Ridge, J. A., Hirata, D., Miranda-Filho, A., Hosny, A., Sanabria, A., Gregoire, V., Patel, S. G., Fagan, J. J., D'Cruz, A. K., Licitra, L., Mehanna, H., Hao, S-P., Psyrri, A., Porceddu, S., Galloway, T. J., Golusinski, W., & 10 othersLee, N. Y., Shiguemori, E. H., Matieli, J. E., Shiguemori, A. P. A. C., Diamantino, L. R., Schiaveto, L. F., Leão, L., Castro, A. F., Carvalho, A. L. & Kowalski, L. P., May 2021, In: Cancer Causes & Control. 32, 5, p. 459-471 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Time-to-Treatment 100%
  • Pandemics 96%
  • Head and Neck Neoplasms 90%
  • Disease Outbreaks 80%
  • Delivery of Health Care 33%

• UK Head and neck cancer surgical capacity during the second wave of the COVID—19 pandemic: have we learned the lessons? COVIDSurg collaborative

  COVIDSurg Collaborative, Jul 2021, In: Clinical Otolaryngology. 46, 4, p. 729-735 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pandemics 100%
  • Head and Neck Neoplasms 94%
  • Ambulatory Care 10%
  • Tertiary Care Centers 9%
  • Critical Care 9%
  1 Citation (Scopus)

  232 Downloads (Pure)

• Ultra-low DNA Input into whole genome methylation assays and detection of oncogenic methylation and copy number variants in circulating tumour DNA

  Whalley, C., Payne, K., Domingo, E., Blake, A., Richman, S., Brooks, J., Batis, N., Spruce, R., Consortium, S. C., Mehanna, H., Nankivell, P. & Beggs, A., 19 Feb 2021, In: Epigenomes. 5, 1, 6.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Circulating Tumor DNA 100%
  • Oncogenic 97%
  • Methylation 62%
  • Genome 47%
  • DNA 38%
  161 Downloads (Pure)

• WEE1 inhibitor: clinical development

  Kong, A. & Mehanna, H., 16 Jul 2021, In: Current oncology reports. 23, 9, 8 p., 107.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Therapy 100%
  • Radiotherapy 70%
  • Clinical Trials 66%
  • Biomarkers 66%
  • atezolizumab 53%
  135 Downloads (Pure)
• 2020

  Acoustofluidic salivary exosome isolation: a liquid biopsy compatible approach for human papillomavirus–associated oropharyngeal cancer detection

  Wang, Z., Li, F., Rufo, J., Chen, C., Yang, S., Li, L., Zhang, J., Cheng, J., Kim, Y., Wu, M., Abemayor, E., Tu, M., Chia, D., Spruce, R., Mehanna, H., Wong, D. T. W. & Huang, T. J., Jan 2020, In: Journal of Molecular Diagnostics. 22, 1, p. 50-59 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Liquid Biopsy 100%
  • Oropharyngeal Neoplasms 94%
  • Exosomes 84%
  • Papilloma 63%
  • Microfluidics 32%
  22 Citations (Scopus)

• Adapting head and neck cancer management in the time of COVID-19

  the Head and Neck International Group (HNCIG) & Mehanna, H., 15 Jul 2020, In: International Journal of Radiation: Oncology - Biology - Physics . 107, 4, p. 628-630

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Citations (Scopus)

  87 Downloads (Pure)

• Circulating tumour cell expression of immune-markers as prognostic and therapeutic biomarkers in head and neck squamous cell carcinoma: a systematic review and meta-analysis

  Payne, K., Pugh, M., Brooks, J., Batis, N., Taylor, G., Nankivell, P. & Mehanna, H., 3 Nov 2020, In: International Journal of Molecular Sciences. 21, 21, p. 1-14 14 p., 8229.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Epithelial Cells 100%
  • biomarkers 85%
  • Biomarkers 80%
  • Circulating Neoplastic Cells 79%
  • Squamous Cell Carcinoma of Head and Neck 71%
  175 Downloads (Pure)

• Comparison of different guidelines for oral cancer

  Köhler, H. F., Mehanna, H., Shah, J. P., Sanabria, A., Fagan, J., Kuriakose, M. A., Rene Leemans, C., O'Sullivan, B., Krishnan, S. & Kowalski, L. P., 15 Oct 2020, (E-pub ahead of print) In: European Archives of Otorhinolaryngology.

  Research output: Contribution to journal › Article › peer-review

  • Mouth Neoplasms 100%
  • Guidelines 58%
  • Squamous Cell Carcinoma 19%
  • Decision Making 18%
  1 Citation (Scopus)

• Concurrent cisplatin or cetuximab with radiotherapy for HPV-positive oropharyngeal cancer: medical resource use, costs, and quality-adjusted survival from the De-ESCALaTE HPV trial

  Mistry, P., Dalby, M., Fulton-Lieuw, T., Kong, A., Dunn, J., Mehanna, H., Gray, A. & Jones, D. A., Jan 2020, In: European Journal of Cancer. 124, p. 178-185 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oropharyngeal Neoplasms 100%
  • Cetuximab 94%
  • Cisplatin 68%
  • Radiotherapy 52%
  • Costs and Cost Analysis 46%
  7 Citations (Scopus)

  138 Downloads (Pure)