Inflammation and Ageing

Projects

Projects per year 1992 2004 2007 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2029

• 1 Not started
• 124 Active
• 846 Finished

Projects per year

Search results

• Finished

  Novartis MTA And Data Sharing - Collaboration Project To Extend The Sjogrens Proteomic Disease Signature

  Fisher, B. (Principal Investigator)

  NOVARTIS PHARMA A.G.

  1/06/24 → 30/11/24

  Project: Industry

• JnJ - single cell analysis of JPsA tissue

  Croft, A. (Principal Investigator)

  JOHNSON & JOHNSON GMBH

  1/05/24 → 31/08/24

  Project: EU

• A single-cell atlas of endolymphatic sac and vestibular neuroepithelium: unlocking the pathophysiology of Meniere's disease and autoimmune inner ear disease

  Croft, A. (Principal Investigator)

  BRITISH MEDICAL ASSOCIATION

  1/12/23 → 30/11/24

  Project: Research

• Phenotyping the novel AA467197-KO mouse

  Clayton, S. (Principal Investigator) & Clark, A. (Co-Investigator)

  Medical Research Council

  1/10/23 → 30/09/24

  Project: Research Councils

• Adaptation and validation of a patient-reported outcome measure of Long COVID symptom burden for adolescents: The Symptom Burden Questionnaire for Long COVID in Young People

  Hughes, S. (Principal Investigator), Haroon, S. (Co-Investigator), Aiyegbusi, L. (Co-Investigator), McMullan, C. (Co-Investigator), Calvert, M. (Co-Investigator) & Sapey, E. (Co-Investigator)

  NIHR

  1/09/23 → 31/08/24

  Project: Other Government Departments

• GSK student placement - Reversing the macrophage-driven inflammation in RA through exploiting glucocorticoid-mediated nodes of inflammation resolution via immunometabolism and HIF-related signalling, with consequences for fibroblast-like sy

  Clark, A. (Principal Investigator)

  Glaxosmithkline

  3/07/23 → 3/10/23

  Project: Industry

• Investigating immune mechanisms underlying ulcerative colitis in the elderly: a pilot observational study

  Duggal, N. (Principal Investigator)

  Crohn's and Colitis Canada

  1/07/23 → 30/06/24

  Project: Research

• BBSRC IAA (2022/23): Xiaoxuan Liu - STANDING Together Globally - an international community for tackling bias in health data

  Kale, A. (Principal Investigator)

  Biotechnology & Biological Sciences Research Council

  1/03/23 → 31/07/23

  Project: Research Councils

• The Human Ageing Genomic Resources

  Lourenco Rocha De Magalhaes, J. P. (Principal Investigator)

  Biotechnology & Biological Sciences Research Council

  1/03/23 → 26/09/23

  Project: Research Councils

• Mechanisms of photobiomodulation as a therapeutic approach for neurotrauma

  Milward, M. (Co-Investigator), Palin, W. (Co-Investigator), Belli, T. (Co-Investigator), Hadis, M. (Co-Investigator), Ahmed, Z. (Co-Investigator) & Stevens, A. (Principal Investigator)

  The Midlands Neurosciences Teaching and Research Fund

  13/02/23 → 13/02/24

  Project: Research

• Cartography - subcontract

  Filer, A. (Principal Investigator)

  JANSSEN PHARMACEUTICA NV

  1/02/23 → 16/09/24

  Project: Research

• TRE-FX: delivering a federated network of TREs to enable safe analytics

  Sapey, E. (Principal Investigator)

  Medical Research Council

  1/02/23 → 31/10/23

  Project: Research Councils

• Improving patient flows through acute medical departments through better patient selection for same day emergency care

  Parekh, D. (Researcher), Sapey, E. (Principal Investigator) & Gkoutos, G. (Co-Investigator)

  Health Data Research UK

  5/01/23 → 31/03/23

  Project: Research

• The role of adipose-derived extracellular vesicles in mediating the obesity associated decline in musculoskeletal health with ageing

  Sagmeister, M. (Co-Investigator), Jones, S. (Principal Investigator), Wijesinghe, S. (Co-Investigator) & Nicholson, T. (Co-Investigator)

  University of Southampton

  3/01/23 → 31/05/23

  Project: Research

• Macroph-ageing and the Susceptibility to infection

  Belchamber, K. (Principal Investigator), Sapey, E. (Co-Investigator), Parekh, D. (Co-Investigator), Cox, M. (Co-Investigator) & Jackson, T. (Co-Investigator)

  THE DUNHILL MEDICAL TRUST

  1/01/23 → 1/07/24

  Project: Research

• Crosstalk between TGF signaling and microRNA machinery in Alzheimer’s disease

  Hill, L. J. (Co-Investigator) & Di Pietro, V. (Principal Investigator)

  ALZHEIMERS RESEARCH UK

  1/12/22 → 30/11/23

  Project: Research

• Linking the skin and joint: defining the cellular basis of tissue tropism in the psoriatic disease spectrum

  Croft, A. (Principal Investigator)

  THE BRITISH SKIN FOUNDATION

  1/12/22 → 30/11/23

  Project: Research

• Development and validation of Rheumatoid Arthritis PredIction moDel using primary care health records [RAPID]

  Falahee, M. (Co-Investigator), Zemedikun, D. (Co-Investigator), Adderley, N. (Co-Investigator), Raza, K. (Principal Investigator) & Nirantharakumar, K. (Co-Investigator)

  NIHR

  1/12/22 → 2/09/24

  Project: Other Government Departments

  • Prodromal Symptoms 100%
  • Aurum 100%
  • Socioeconomic Status 100%
  • Primary Care Database 100%
  • Rheumatoid Arthritis 100%

• Regional provision of a nanostring CosMx spatial molecular imager

  Pugh, M. (Co-Investigator), Jones, S. (Co-Investigator), Gardner, D. (Co-Investigator), Croft, A. (Co-Investigator), Willcox, B. (Co-Investigator), Willcox, B. (Co-Investigator), Moss, P. (Co-Investigator) & Filer, A. (Principal Investigator)

  Medical Research Council

  31/10/22 → 31/03/23

  Project: Research Councils

• MRC CiC: Detection of moderate to severe traumatic brain injury in the eye: A proof of concept

  Belli, T. (Co-Investigator), Goldberg Oppenheimer, P. (Co-Investigator) & Blanch, R. (Principal Investigator)

  Medical Research Council

  1/10/22 → 31/03/23

  Project: Research Councils

• Development of a spinal-optical interface for diagnostics and therapeutics

  Belli, T. (Co-Investigator) & Ahmed, Z. (Principal Investigator)

  ROYAL COLLEGE OF SURGEONS

  1/10/22 → 30/09/23

  Project: Research

• MRC CiC: De-risking pilot study for targeted delivery of oligonucleotide therapeutics using conjugated antibodies into musculoskeletal cells of the human joint

  Jones, S. (Principal Investigator) & Hardy, R. (Co-Investigator)

  Medical Research Council

  1/10/22 → 31/03/23

  Project: Research Councils

• MRC CiC: Developing novel mitochondrial-targeted therapies for stem-cell rejuvenation

  Wallace, G. (Co-Investigator), Romero, J. (Principal Investigator), Rauz, S. (Co-Investigator) & Lord, J. (Co-Investigator)

  Medical Research Council

  1/10/22 → 31/03/23

  Project: Research Councils

• GeneFriends: A gene and transcript co-expression resource

  Lourenco Rocha De Magalhaes, J. P. (Principal Investigator)

  The Wellcome Trust

  1/09/22 → 28/08/24

  Project: Research

  • Aging 100%
  • Human Aging 68%
  • Software Design 45%
  • Mouse Atlas 45%
  • Stemness 45%

• Evaluation Of The Concussion Substitution Protocol In Football

  Belli, T. (Principal Investigator) & Di Pietro, V. (Co-Investigator)

  THE FOOTBALL ASSOCIATION LTD

  1/08/22 → 31/10/24

  Project: Research

• Bayer healthy ageing collaboration - vitamins for healthy older adults to see if it can reduce their biological age

  Lord, J. (Principal Investigator) & Jackson, T. (Co-Investigator)

  BAYER

  1/08/22 → 30/06/24

  Project: EU

• World HIp Trauma Evaluation [WHITE]: Delirium and Cognitive Impairment [DeCI]

  Jackson, T. (Principal Investigator)

  NIHR CENTRAL COMMISSIONING FACILITY

  1/07/22 → 31/05/24

  Project: Other Government Departments

• Understanding the role of autophagy on the long-lasting effects of obesity on Atherosclerosis [Sub-project of 21502]

  Niven, J. (Principal Investigator)

  British Heart Foundation

  1/07/22 → 31/07/23

  Project: Research

• The use of PEPITEM and its novel peptido-mimetics for the treatment of autoimmune and chronic inflammatory diseases

  Rainger, E. (Principal Investigator), Iqbal, A. J. (Co-Investigator) & McGettrick, H. (Co-Investigator)

  ARTHRITIS RESEARCH UK

  1/07/22 → 31/10/23

  Project: Research

• CONTACTS study

  Belli, T. (Principal Investigator)

  METCHLEY PARK MEDICAL SOCIETY

  1/07/22 → 14/08/23

  Project: Research

• Parasternal nerve block trial

  Slinn, G. (Co-Investigator), Gao Smith, F. (Principal Investigator), Cheed, V. (Researcher) & Middleton, L. (Researcher)

  NIHR EVALUATION, TRIALS AND STUDIES COORDINATING CENTRE

  1/05/22 → 30/04/24

  Project: Other Government Departments

• Targeting pathogenic fibroblasts in immune mediated inflammatory diseases

  Croft, A. (Principal Investigator)

  ARTHRITIS RESEARCH UK

  1/05/22 → 30/04/23

  Project: Research

• Digoxin as a novel senolytic: secondary analysis of the RATE-AF Randomised Clinical Trial

  Bunting, K. (Co-Investigator), Jackson, T. (Principal Investigator), Lord, J. (Co-Investigator), Kotecha, D. (Co-Investigator) & Wilson, D. (Co-Investigator)

  BRITISH GERIATRICS SOCIETY

  1/04/22 → 31/12/23

  Project: Research

• Rejuvenating mitochondria to alleviate premature senescence and multimorbidity in diabetes

  Romero, J. (Principal Investigator), Lord, J. (Co-Investigator) & Narendran, P. (Co-Investigator)

  EUROPEAN FOUNDATION FOR THE STUDY OF DIABETES

  1/03/22 → 31/12/23

  Project: Research

• CARINA: catalyst reducing immune ageing

  Lord, J. (Principal Investigator)

  Biotechnology & Biological Sciences Research Council

  14/02/22 → 13/02/24

  Project: Research Councils

• Wellcome TDF: Photobiomodulation and Raman spectroscopy: development of a direct-to-brain therapeutic/diagnostic device for neurotrauma

  Goldberg Oppenheimer, P. (Co-Investigator), Belli, T. (Principal Investigator), Milward, M. (Co-Investigator), Ahmed, Z. (Co-Investigator), Hadis, M. (Co-Investigator) & Palin, W. (Co-Investigator)

  The Wellcome Trust

  7/02/22 → 5/10/22

  Project: Research

• Optimised Inhalers to Reduce COPD Exacerbation Re-admissions and Mortality: a Feasibility Study

  Sapey, E. (Principal Investigator)

  NIHR

  1/02/22 → 31/07/23

  Project: Other Government Departments

• DARE: creating the blueprint for a federated network of next generation, cross-council Trusted Research Environments

  Sapey, E. (Principal Investigator) & Newsome, P. (Co-Investigator)

  Medical Research Council

  4/01/22 → 31/08/22

  Project: Research Councils

• WT ISSF: Hannah Botfield Continuity award 2020

  Botfield, H. (Principal Investigator)

  The Wellcome Trust

  1/01/22 → 30/09/22

  Project: Research

• Investigating neutrophil function in COVID and non COVID pneumonia

  Thickett, D. (Principal Investigator) & Parekh, D. (Co-Investigator)

  Uhb Nhs Trust

  1/11/21 → 31/10/22

  Project: Research

• WT ISSF 2021 (R9): Saba Nayar High Impact Publications Award

  Nayar, S. (Principal Investigator)

  The Wellcome Trust

  1/10/21 → 30/09/22

  Project: Research

• Inflammatory arthritis research programme

  Raza, K. (Principal Investigator) & Falahee, M. (Co-Investigator)

  Sandwell & West Birmingham Hospitals

  1/10/21 → 31/03/24

  Project: Research

• WT ISSF 2021 (R9): Sally Clayton Pilot Data Award

  Clayton, S. (Principal Investigator)

  The Wellcome Trust

  1/10/21 → 30/09/22

  Project: Research

• Defining the cellular basis of disease persistence in juvenile idiopathic arthritis

  Raza, K. (Co-Investigator), Filer, A. (Co-Investigator), Buckley, C. (Co-Investigator) & Croft, A. (Principal Investigator)

  ARTHRITIS RESEARCH UK

  1/10/21 → 30/09/24

  Project: Research

• Evaluating the impact of E-cigarettes on the innate immune response in chronic obstructive pulmonary disease

  Sapey, E. (Co-Investigator), Thickett, D. (Co-Investigator) & Scott, A. (Principal Investigator)

  BRITISH LUNG FOUNDATION

  1/10/21 → 30/09/24

  Project: Research

  • Neutrophil Activation 100%
  • Vitamin D 81%
  • Observational Cohort Study 81%
  • Sepsis 81%
  • Pneumonia 81%

• Genetic and cellular dysfunction of skeletal muscle following high-energy trauma

  Jones, S. (Principal Investigator)

  Royal Centre For Defence Medicine

  1/09/21 → 28/02/23

  Project: Research

• Serine proteinase footprints and alpha-1 antitrypsin deficiency

  Sapey, E. (Principal Investigator) & Stockley, R. (Co-Investigator)

  CSL Behring

  10/08/21 → 30/08/23

  Project: Industry

• Extracellular vesicles in thermal injury as novel mediators of inflammation and organ damage [Sub-award of 1001749]

  Lord, J. (Co-Investigator) & Harrison, P. (Principal Investigator)

  KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH

  1/08/21 → 31/07/24

  Project: Research

• Parsing the anti-inflammatory and immuno-suppressive effects of glucocorticoids [Sub-award of 1001749]

  Sapey, E. (Co-Investigator), Clark, A. (Principal Investigator), Hardy, R. (Co-Investigator) & Parekh, D. (Co-Investigator)

  KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH

  1/08/21 → 31/07/24

  Project: Research

• Hip fracture lidocaine IV trial (HIP-LIT): a feasibility study for a randomised controlled trial of the effect of intravenous lidocaine at the time of surgery on outcomes following hip fracture

  Jackson, T. (Principal Investigator)

  NIHR

  1/08/21 → 3/07/23

  Project: Other Government Departments